Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | $ 970.00 |
Description | MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability. |
In vivo | MPC-0767 (oral adminstration; 265 mg/kg; single dose) exhibits a improved PK property, the T max , C max , AUC and F% are 1?(h), 21562 ng/mL, 94194 h*ng/mL and 56%, respectively[1].MPC-0767 (oral adminstration; 265 mg/kg) demonstrates comparable efficacy in an N-87 xenograft tumor model, the 46% tumor size reduction with no evidence of weight loss in the study animals[1].MPC-0767 is well tolerated when administered at 252?mg/kg po (equivalent to 200?mg/kg dose of?MPC-3100)[1]. |
Molecular Weight | 734.64 |
Formula | C26H36BrN7O9S2 |
CAS No. | 1310540-32-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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MPC-0767 1310540-32-9 MPC0767 MPC 0767 inhibitor inhibit