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Anti-Alpha-Synuclein Antibody (2M749)
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Catalog No. TMAC-00163
Alias PD1, PARK4, PARK1, NACP
Anti-Alpha-Synuclein Antibody (2M749) is a Rabbit antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (2M749) can be used in FCM,ICC,IF,IHC,IP,WB.
Anti-Alpha-Synuclein Antibody (2M749)
Anti-Alpha-Synuclein Antibody (2M749)
😃Good
Catalog No. TMAC-00163Alias PD1, PARK4, PARK1, NACP
Anti-Alpha-Synuclein Antibody (2M749) is a Rabbit antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (2M749) can be used in FCM,ICC,IF,IHC,IP,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Alpha-Synuclein Antibody (2M749) is a Rabbit antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (2M749) can be used in FCM,ICC,IF,IHC,IP,WB. |
| Synonyms | PD1, PARK4, PARK1, NACP |
| Ig Type | IgG |
| Clone | 2M749 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of Alpha Synuclein on human fetal brain tissue lysate using anti-Alpha Synuclein antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Alpha Synuclein antibody. Counter stained with hematoxylin. 3. ICC staining Alpha Synuclein in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of SH-SY-5Y cells with Alpha Synuclein antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The synuclein family members, including α-synuclein (also designated NACP for non-β-Amyloid component) and β-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-synuclein is localized to neuronal cell bodies and synapses. α-synuclein was first identified as a component of Alzheimer's disease amyloid plaques. Abnormal platelet function in Alzheimer's disease has been demonstrated. During megakaryocytic differentiation α-synuclein has been found to be upregulated, while β-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of α-synuclein has been found in patients with early onset Parkinson's disease. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 16 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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