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Anti-Beta-casein Polyclonal Antibody 2 (Synonyms: Csn2, CASB)
Catalog No. TMAB-00228 Copy Product Info
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Anti-Beta-casein Polyclonal Antibody 2 is a Rabbit antibody targeting Beta-casein. Anti-Beta-casein Polyclonal Antibody 2 can be used in WB.
Anti-Beta-casein Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-00228
Synonyms Csn2, CASB
Anti-Beta-casein Polyclonal Antibody 2 is a Rabbit antibody targeting Beta-casein. Anti-Beta-casein Polyclonal Antibody 2 can be used in WB.
Anti-Beta-casein Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Beta-casein Polyclonal Antibody 2 is a Rabbit antibody targeting Beta-casein. Anti-Beta-casein Polyclonal Antibody 2 can be used in WB. |
| Synonyms | Csn2, CASB |
| Ig Type | IgG |
| Reactivity | Human,Cow,Goat (predicted:Sheep) |
| Verified Activity | 1. Sample: Lane 1: Milk (Goat) Lysate at 2 μg Lane 2: Milk (Cow) Lysate at 30 μg Lane 3: Milk (Cow) Lysate at 3 μg Lane 4: Milk (Human) Lysate at 30 μg Primary: Anti-Beta-casein (TMAB-00228) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25-29 kDa Observed band size: 25-29 kDa 2. Sample: Lane 1: Milk (Cow) Lysate at 40 μg Primary: Anti-Beta-casein (TMAB-00228) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24 kDa Observed band size: 24 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Mammary gland specific. Secreted in milk. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Milk proteins are crucial for the development of all newborn mammals and caseins constitute the major proteins in mammalian milk. b- and k-caseins are the only caseins present in human milk. The b-casein/k-casein ratio is higher in colostrum than in transitional and mature milk and is related to a better digestibility of colostrum casein micelles by the neonate during the first days of life. Human b-casein-encoding gene (Bca) contains a highly phosphorylated site, which is responsible for the calcium-binding capacity of b-casein. A common set of transcription factors are required for the expression of b-casein. Multiple binding sites for Stat5, C/EBPb (CCAAT/enchancer-binding protein) and several half-sites for glucocorticoid receptor (GR) are identified in the distal human enhancer of the b-casein gene. b-casein gene transcription is regulated primarily by a composite response element (CoRE), which integrates signaling from the lactogenic hormones PRL, insulin and hydrocortisone in mammary epithelial cells. NFkB functions as a negative regulator of b-casein gene expression during pregnancy by interfering with Stat5 tyrosine phosphorylation |
| Immunogen | KLH conjugated synthetic peptide: cow Beta-casein |
| Antigen Species | Cow |
| Gene Name | CSN2 |
| Protein Name | beta-casein |
| Biology Area | Pol II Transcription,Transcription Factors,Coat Proteins |
| Function | Important role in determination of the surface properties of the casein micelles. Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity. |
| Molecular Weight | Theoretical: 24 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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