Influenza Proteins

Influenza A H1N1 (A Michigan 45 2015) Neuraminidase NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa.

Influenza A H1N1 (A New York 1 1918) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q9WFX4.

Influenza B (B Austria 1359417 2021) Nucleoprotein NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 63 kDa.

Influenza A H5N1 (A Cambodia R0405050 2007) Hemagglutinin HA Protein (HA1+HA2, uncleaved, GRRKKR to TETR, aa 1-531, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is B6EBW8.

Influenza A H5N1 (A VietNam 1203 2004) Hemagglutinin HA Protein (His & Fc) is expressed in HEK293 mammalian cells with His and Fc tag. The predicted molecular weight is 85.7 kDa and the accession number is Q5EP31.

Influenza A H1N1 (A Puerto Rico 8 1934) Hemagglutinin HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03452.

Influenza A H1N1 (A Puerto Rico 8 34 Mount Sinai) Nucleoprotein NP Protein (I116M, His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P03466.

Influenza A H3N2 (A Victoria 361 2011) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is L0HR89.

Influenza A H1N1 (A Beijing 22808 2009) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is D3YSI0.

Influenza A H7N9 (A Anhui 1 2013) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa.

Influenza A H1N1 (A WSN 1933) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.1 kDa and the accession number is B4URE7.

Influenza A H1N1 (A California 04 2009) Neuraminidase NA is expressed in HEK293 mammalian cells. The predicted molecular weight is 47.8 kDa and the accession number is C3W5S3.

Influenza B (strain B Lee 1940) Nucleoprotein NP Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.8 kDa and the accession number is P04665.

Influenza A H13N8 (A black-headed gull Netherlands 1 00) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is Q5DL26.

Influenza A H5N1 (A chicken VietNam NCVD-016 2008) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is C4P278.

Influenza A H11N2 (A thick-billed murre Newfoundland 031 2007) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa.

Influenza A H7N1 (A turkey Italy 4602 99) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q7TAW6.

Binds and inhibits the conjugation of the ubiquitin-like G1P2 ISG15 protein to its target proteins. Since G1P2 ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response. Prevents EIF2AK2 PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2 PKR. Also binds poly(A) and U6 snRNA.

Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.

Influenza A H1N1 (A Texas 36 1991) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.1 kDa and the accession number is B4UPL3.

Influenza A H6N2 (A chicken Guangdong C273 2011) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.6 kDa and the accession number is I6PXD2.

Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 1 virus (HPIV-1) Nucleoprotein NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 63.6 kDa and the accession number is P24304.

Influenza A H1N1 (A USSR 90 1977) Neuraminidase NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P03469.2.

Influenza A H1N1 (A Puerto Rico 8 1934) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is P03452.

Influenza A H1N1 (A Texas 05 2009) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C3W5V3.

Influenza A H3N2 (A Hong Kong 1 1968) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q91MA7.

Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1 XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.

Influenza A H3N2 (strain A X-31) Polymerase acidic Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.6 kDa and the accession number is Q9IQ47.

Influenza A H3N2 (A Aichi 2 1968) Matrix protein 1 M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is I6SGW5.

Influenza A H5N1 (A Anhui 1 2005) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q1WDM0.

Influenza A H3N2 Neuraminidase NA Protein (E119V) is expressed in HEK293 mammalian cells. The accession number is C0LU95.

Influenza A H5N1 (A Indonesia 5 2005) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is A8HWY8.

Influenza A H5N1 (A Anhui 1 2005) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q1WDM0.

Influenza A H3N2 (A Victoria 208 2009) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa.

Influenza A H2N2 (A Canada 720 2005) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q4ZH98.

Influenza A H3N2 (A Victoria 208 2009) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.2 kDa.

Influenza A H3N2 (A Moscow 10 1999) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is Q1NZ37.

Influenza A H1N1 (A Brevig Mission 1 1918) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.6 kDa and the accession number is Q9WFX3.

Influenza A H2N2 (A Canada 720 2005) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is Q4ZH98.

Influenza A H5N1 (A Hong Kong 483 1997) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.8 kDa and the accession number is O92930.

Influenza A H5N1 (A duck Hunan 795 2002) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is B1MPL4.

Influenza A H1N2 (A swine Guangxi 13 2006) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is A5JQC7.

Influenza A H1N1 (A New Caledonia 20 1999) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q6WG00.

Influenza A H6N1 (A northern shoveler California HKWF115 2007) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is B3RDB8.

Influenza A H7N7 (A chicken Netherlands 1 03) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is Q6VMK2.

Influenza A H2N2 (A Ann Arbor 6 1960) Nucleoprotein NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P21433-1.

Influenza A H3N2 Neuraminidase NA Protein is expressed in HEK293 mammalian cells. The accession number is C0LU95.

Influenza A H1N3 (A duck NZL 160 1976) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.9 kDa and the accession number is Q20PD6.