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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases. Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Library Customization | TargetMol Library Composition

Apoptosis
NF-κB
Autophagy
PI3K
EGFR
HDAC
Wnt/beta-catenin
mTOR
JAK
Akt
STAT
FLT
AMPK
GSK-3
Antibacterial
VEGFR
Bcl-2 Family
Endogenous Metabolite
CDK
c-Kit
Proteasome
Bcr-Abl
PDGFR
HIF/HIF Prolyl-Hydroxylase
Histone Methyltransferase
Src
HIF
ERK
Dehydrogenase
COX
Tyrosine Kinases
Potassium Channel
Hedgehog/Smoothened
DNA/RNA Synthesis
Antibiotic
HIV Protease
DNA-PK
Reactive Oxygen Species
FGFR
S6 Kinase
Parasite
Caspase
Epigenetic Reader Domain
TNF
p38 MAPK
ATM/ATR
HER
Topoisomerase
DNA Methyltransferase
PKC
PARP
IL Receptor
PDK
JNK
Pim
Ferroptosis
c-Met/HGFR
Mitophagy
PPAR
Aurora Kinase
Gamma-secretase
Influenza Virus
c-RET
Microtubule Associated
PD-1/PD-L1
c-Myc
BTK
Raf
ALK
Antifungal
Virus Protease
MEK
IGF-1R
Cytochromes P450
MAPK
TAM Receptor
E1/E2/E3 Enzyme
DPP-4
CXCR
PI4K
PKA
Calcium Channel
Nrf2
p53
Histone Demethylase
Smo
Trk receptor
c-Fms
AChR
Syk
NO Synthase
Antioxidant
Nucleoside Antimetabolite/Analog
Chk
Antiviral
Casein Kinase
HCV Protease
Phosphatase
Isocitrate Dehydrogenase (IDH)
Lipoxygenase
IκB/IKK
Beta Amyloid
MMP
Interleukin
TLR
PLK
NOS
PDE
ROS
P-gp
HSP
Sodium Channel
Adenosine Receptor
CSF-1R
SIK
Drug Metabolite
FAK
DYRK
ROCK
Mitochondrial Metabolism
Antifection
PTEN
Histone Acetyltransferase
5-HT Receptor
GABA Receptor
Rho
Cysteine Protease
DNA Alkylation
HSV
DUB
TGF-beta/Smad
Prostaglandin Receptor
MELK
Anti-infection
IRAK
Mdm2
Integrin
DNA Alkylator/Crosslinker
HBV
Adrenergic Receptor
IAP
GluR
SARS-CoV
Aminopeptidase
Sirtuin
transporter
Retinoid Receptor
Cannabinoid Receptor
Ras
Tyrosinase
ROS Kinase
Chloride channel
ATPase
Carbonic Anhydrase
Estrogen/progestogen Receptor
Histamine Receptor
Immunology/Inflammation related
IRE1
Glucosidase
Cholinesterase (ChE)
CaMK
MNK
Porcupine
SGK
S1P Receptor
ADC Cytotoxin
DHFR
Dopamine Receptor
LTR
BACE
IFNAR
RAAS
Tie-2
GTPase
Serine/threonin kinase
TRP/TRPV Channel
MAO
UGT
LDL
NMDAR
Opioid Receptor
PAK
ACK1
Lipid
BCRP
PGE Synthase
Ephrin Receptor
Methionine Adenosyltransferase (MAT)
Reverse Transcriptase
Adenosine Deaminase
NOD
Thrombin
NOD-like Receptor (NLR)
MLK
Kinesin
GPCR
Transferase
NEDD8
CRM1
NADPH
PERK
Glutathione Peroxidase
TOPK
Estrogen Receptor/ERR
Cholecystokinin Receptor
Hck
Antifolate
Serine Protease
Liver X Receptor
Leukotriene Receptor
NAMPT
PYK2
Aryl Hydrocarbon Receptor
RIP kinase
GRK
Monoamine Transporter
Fatty Acid Synthase
CCR
KSP
cAMP
Androgen Receptor
SGLT
ATP Citrate Lyase
Beta-Secretase
Acyltransferase
Survivin
Hippo pathway
CRISPR/Cas9
Phospholipase
Discoidin Domain Receptor (DDR)
AhR
Melanin-concentrating Hormone Receptor (MCHR)
Proton pump
PROTACs
Adenylyl Cyclase
MicroRNA
Monocarboxylate transporter
NPC1L1
RAR/RXR
MALT
ROR
NUDIX hydrolase
Amino Acids and Derivatives
MyD88
YAP
Arginase
LPL Receptor
Reductase
Na+/Ca2+ Exchanger
Lipase
gp120/CD4
Factor Xa
Progesterone Receptor
OCT
MRP
FXR
Glucokinase
Glutaminase
Glucocorticoid Receptor
Myosin
Haspin Kinase
DNA gyrase
ABC Transporter
Guanylate cyclase
PAD
Thrombopoietin Receptor
DNA
Telomerase
Wee1
OXPHOS
STING
LRRK2
Free radical scavengers
Decarboxylase
hCE
RSV
Neprilysin
GST
Protease
Aromatase
KLF
Cuproptosis
DAPK
Platelet aggregation
NADPH-oxidase
BMI-1
Sigma receptor
Protease-activated Receptor
p97
CFTR
Imidazoline Receptor
Monoamine Oxidase
PKM