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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases.

Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
NF-κB
PI3K
EGFR
HDAC
Wnt/beta-catenin
mTOR
JAK
Akt
STAT
Endogenous Metabolite
FLT
Antibacterial
AMPK
Bcl-2 Family
GSK-3
VEGFR
HIF/HIF Prolyl-Hydroxylase
CDK
c-Kit
Proteasome
Bcr-Abl
PDGFR
Histone Methyltransferase
Src
ERK
COX
Dehydrogenase
HIF
Parasite
Reactive Oxygen Species
DNA/RNA Synthesis
Potassium Channel
p38 MAPK
Caspase
Antibiotic
HIV Protease
Tyrosine Kinases
S6 Kinase
Hedgehog/Smoothened
FGFR
TNF
DNA-PK
Epigenetic Reader Domain
PARP
ATM/ATR
JNK
Virus Protease
DNA Methyltransferase
HER
PKC
c-Met/HGFR
Topoisomerase
PPAR
Interleukin
Microtubule Associated
Ferroptosis
Mitophagy
Aurora Kinase
PDK
c-Myc
IL Receptor
Pim
Gamma-secretase
c-RET
PD-1/PD-L1
Antifungal
BTK
Cytochromes P450
Influenza Virus
Raf
Smo
IGF-1R
ALK
Isocitrate Dehydrogenase (IDH)
MAPK
MEK
Nucleoside Antimetabolite/Analog
NO Synthase
Calcium Channel
PI4K
TAM Receptor
Histone Demethylase
PKA
DPP-4
Nrf2
c-Fms
MDM-2/p53
Ras
Phosphatase
E1/E2/E3 Enzyme
CXCR
Casein Kinase
p53
MMP
Trk receptor
IκB/IKK
Beta Amyloid
Syk
HCV Protease
Antioxidant
Chk
Antiviral
TLR
AChR
Lipoxygenase
HSP
SARS-CoV
PDE
Drug Metabolite
ROS
HSV
P-gp
PLK
Mitochondrial Metabolism
TGF-beta/Smad
Histone Acetyltransferase
Sodium Channel
NOS
Adenosine Receptor
DYRK
ROCK
CSF-1R
SIK
Antifection
PTEN
5-HT Receptor
Anti-infection
FAK
OXPHOS
Sirtuin
GABA Receptor
Tyrosinase
ROS Kinase
Integrin
DNA Alkylator/Crosslinker
Tie-2
Bcl-6
Rho
Cysteine Protease
TRP/TRPV Channel
IAP
DNA Alkylation
DUB
Prostaglandin Receptor
Aminopeptidase
MELK
Reverse Transcriptase
Cannabinoid Receptor
IRAK
Mdm2
ATPase
HBV
Adrenergic Receptor
Immunology/Inflammation related
Glucosidase
CaMK
Porcupine
transporter
Retinoid Receptor
SGK
NOD-like Receptor (NLR)
Carbonic Anhydrase
Estrogen/progestogen Receptor
Histamine Receptor
Estrogen Receptor/ERR
Serine Protease
Aryl Hydrocarbon Receptor
IRE1
Cholinesterase (ChE)
GluR
PGE Synthase
MNK
Survivin
Kinesin
S1P Receptor
Monoamine Oxidase
ADC Cytotoxin
GPCR
Chloride channel
DHFR
Dopamine Receptor
CRM1
LTR
Reductase
BACE
IFNAR
RAAS
PERK
GTPase
Antifolate
Serine/threonin kinase
NAMPT
MAO
UGT
LDL
Opioid Receptor
PAK
ACK1
Thrombopoietin Receptor
ATP Citrate Lyase
Lipid
BCRP
Acyltransferase
Ephrin Receptor
Methionine Adenosyltransferase (MAT)
Hippo pathway
FKBP
Adenosine Deaminase
NOD
Thrombin
MLK
IKZF
Proton pump
PROTACs
Transferase
NEDD8
Amino Acids and Derivatives
MyD88
LPL Receptor
NADPH
Glutathione Peroxidase
TOPK
Cholecystokinin Receptor
Hck
Liver X Receptor
Leukotriene Receptor
FXR
PYK2
Myosin
RIP kinase
GRK
NMDAR
Monoamine Transporter
Fatty Acid Synthase
CCR
Angiotensin-converting Enzyme (ACE)
KSP
cAMP
Androgen Receptor
Telomerase
SGLT
Wee1
Beta-Secretase
CRISPR/Cas9
Phospholipase
Cuproptosis
Discoidin Domain Receptor (DDR)
DAPK
AhR
PGK1
Melanin-concentrating Hormone Receptor (MCHR)
Adenylyl Cyclase
MicroRNA
NPC1L1
Monocarboxylate transporter
RAR/RXR
CD38
MALT
ROR
NUDIX hydrolase
Y Box Binding Protein 1
YAP
Arginase
Na+/Ca2+ Exchanger
Lipase
Necroptosis
gp120/CD4
Factor Xa
Progesterone Receptor
OCT
MRP
Glucokinase
Glutaminase
NR4A
RANKL/RANK
Glucocorticoid Receptor
Prolyl Endopeptidase (PREP)
PAFR
Haspin Kinase
DNA gyrase
ABC Transporter
Na-K-Cl cotransporter
Guanylate cyclase
FAAH
PAD
Cadherin
DNA
STING
LRRK2
Free radical scavengers
Urea Transporter
AIM2
Decarboxylase
hCE
Pyroptosis
RSV
Neprilysin
GST
Kras
Protease
Aromatase
KLF
Hydroxylase
Platelet aggregation
NADPH-oxidase
BMI-1
Sigma receptor
Protease-activated Receptor
p97
Liposome
CFTR
Imidazoline Receptor
PKM
Ferroportin

Keywords