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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases. Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
NF-κB
PI3K
EGFR
HDAC
Wnt/beta-catenin
mTOR
Akt
JAK
STAT
FLT
Endogenous Metabolite
Antibacterial
AMPK
Bcl-2 Family
GSK-3
VEGFR
HIF/HIF Prolyl-Hydroxylase
CDK
c-Kit
Bcr-Abl
Proteasome
Histone Methyltransferase
PDGFR
Src
ERK
Dehydrogenase
COX
HIF
Parasite
Reactive Oxygen Species
Potassium Channel
DNA/RNA Synthesis
p38 MAPK
Antibiotic
Caspase
HIV Protease
S6 Kinase
Tyrosine Kinases
Hedgehog/Smoothened
TNF
FGFR
DNA-PK
Epigenetic Reader Domain
ATM/ATR
Virus Protease
DNA Methyltransferase
HER
PARP
PKC
JNK
Topoisomerase
c-Met/HGFR
Microtubule Associated
PPAR
Mitophagy
PDK
Interleukin
IL Receptor
Ferroptosis
c-Myc
Aurora Kinase
c-RET
Gamma-secretase
Pim
PD-1/PD-L1
Influenza Virus
Antifungal
BTK
Smo
Raf
Cytochromes P450
ALK
MAPK
IGF-1R
Isocitrate Dehydrogenase (IDH)
MEK
Nucleoside Antimetabolite/Analog
Calcium Channel
TAM Receptor
PI4K
Nrf2
NO Synthase
PKA
DPP-4
c-Fms
Ras
MDM-2/p53
Phosphatase
CXCR
p53
E1/E2/E3 Enzyme
Casein Kinase
IκB/IKK
MMP
Trk receptor
Syk
Beta Amyloid
Histone Demethylase
AChR
Chk
Antiviral
HCV Protease
TLR
Antioxidant
HSP
SARS-CoV
Lipoxygenase
Drug Metabolite
PLK
PDE
P-gp
TGF-beta/Smad
Mitochondrial Metabolism
HSV
Histone Acetyltransferase
Sodium Channel
Antifection
FAK
CSF-1R
SIK
ROS
ROCK
5-HT Receptor
Anti-infection
NOS
PTEN
Adenosine Receptor
DYRK
OXPHOS
Tyrosinase
Sirtuin
GABA Receptor
ROS Kinase
Aminopeptidase
Integrin
Tie-2
DNA Alkylation
DUB
Bcl-6
TRP/TRPV Channel
DNA Alkylator/Crosslinker
Cysteine Protease
Prostaglandin Receptor
Cannabinoid Receptor
IAP
Rho
MELK
Reverse Transcriptase
IRAK
Glucosidase
Immunology/Inflammation related
Adrenergic Receptor
transporter
SGK
Retinoid Receptor
ATPase
HBV
Porcupine
Mdm2
Estrogen/progestogen Receptor
PGE Synthase
Survivin
Kinesin
Histamine Receptor
Serine Protease
MNK
S1P Receptor
CaMK
NOD-like Receptor (NLR)
Monoamine Oxidase
Aryl Hydrocarbon Receptor
IRE1
Carbonic Anhydrase
Cholinesterase (ChE)
GluR
ADC Cytotoxin
Dopamine Receptor
CRM1
Antifolate
UGT
Thrombopoietin Receptor
BCRP
Methionine Adenosyltransferase (MAT)
DHFR
RAAS
Estrogen Receptor/ERR
Acyltransferase
Adenosine Deaminase
IFNAR
BACE
ACK1
Lipid
Thrombin
Chloride channel
Serine/threonin kinase
LDL
Opioid Receptor
FKBP
MLK
LTR
ATP Citrate Lyase
Hippo pathway
GPCR
GTPase
NAMPT
MAO
PAK
Ephrin Receptor
NOD
IKZF
LPL Receptor
PYK2
RIP kinase
Fatty Acid Synthase
Androgen Receptor
Wee1
Cuproptosis
Discoidin Domain Receptor (DDR)
DAPK
Reductase
TOPK
Cholecystokinin Receptor
Myosin
Beta-Secretase
Phospholipase
Amino Acids and Derivatives
NMDAR
Angiotensin-converting Enzyme (ACE)
Transferase
NADPH
Hck
GRK
Telomerase
SGLT
AhR
Proton pump
MyD88
Glutathione Peroxidase
Leukotriene Receptor
FXR
KSP
PROTACs
NEDD8
PERK
Monoamine Transporter
CCR
CRISPR/Cas9
Liver X Receptor
cAMP
PGK1
Adenylyl Cyclase
MRP
Glutaminase
PAD
Urea Transporter
Protease-activated Receptor
p97
Melanin-concentrating Hormone Receptor (MCHR)
NPC1L1
Decarboxylase
Neprilysin
Liposome
MicroRNA
ROR
Lipase
Glucokinase
PAFR
Haspin Kinase
RSV
Protease
KLF
NUDIX hydrolase
YAP
Necroptosis
OCT
RANKL/RANK
Glucocorticoid Receptor
Na-K-Cl cotransporter
hCE
BMI-1
Monocarboxylate transporter
RAR/RXR
MALT
Prolyl Endopeptidase (PREP)
DNA gyrase
Guanylate cyclase
Cadherin
STING
LRRK2
Free radical scavengers
Pyroptosis
NADPH-oxidase
PKM
CD38
NR4A
ABC Transporter
FAAH
DNA
Kras
Hydroxylase
Sigma receptor
CFTR
Imidazoline Receptor
Y Box Binding Protein 1
Arginase
Na+/Ca2+ Exchanger
gp120/CD4
Factor Xa
Progesterone Receptor
AIM2
GST
Aromatase
Platelet aggregation
Ferroportin

Keywords