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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases. Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
NF-κB
Autophagy
PI3K
EGFR
HDAC
Wnt/beta-catenin
JAK
mTOR
Akt
STAT
FLT
AMPK
GSK-3
Antibacterial
Endogenous Metabolite
VEGFR
Bcl-2 Family
CDK
c-Kit
Proteasome
Bcr-Abl
HIF/HIF Prolyl-Hydroxylase
PDGFR
Histone Methyltransferase
Src
HIF
ERK
Dehydrogenase
COX
Tyrosine Kinases
Potassium Channel
DNA/RNA Synthesis
Hedgehog/Smoothened
Antibiotic
DNA-PK
FGFR
HIV Protease
Reactive Oxygen Species
S6 Kinase
Caspase
Epigenetic Reader Domain
TNF
ATM/ATR
p38 MAPK
Parasite
HER
DNA Methyltransferase
Topoisomerase
PKC
IL Receptor
PARP
PDK
JNK
Pim
Aurora Kinase
c-Met/HGFR
Ferroptosis
Mitophagy
PPAR
c-RET
Gamma-secretase
Influenza Virus
Microtubule Associated
PD-1/PD-L1
BTK
c-Myc
ALK
Raf
Antifungal
MEK
Virus Protease
Cytochromes P450
IGF-1R
MAPK
TAM Receptor
CXCR
DPP-4
PI4K
Calcium Channel
E1/E2/E3 Enzyme
Nrf2
p53
PKA
c-Fms
Histone Demethylase
NO Synthase
Nucleoside Antimetabolite/Analog
Smo
Syk
Trk receptor
AChR
Antioxidant
Antiviral
Casein Kinase
Chk
Beta Amyloid
HCV Protease
Interleukin
Isocitrate Dehydrogenase (IDH)
IκB/IKK
Lipoxygenase
Phosphatase
PLK
TLR
Drug Metabolite
HSP
MMP
PDE
P-gp
ROS
Sodium Channel
Adenosine Receptor
CSF-1R
FAK
NOS
SIK
5-HT Receptor
Antifection
DYRK
Histone Acetyltransferase
Mitochondrial Metabolism
PTEN
ROCK
Anti-infection
Cysteine Protease
DNA Alkylation
DUB
GABA Receptor
HSV
IRAK
MELK
Prostaglandin Receptor
Rho
TGF-beta/Smad
Adrenergic Receptor
Aminopeptidase
Cannabinoid Receptor
DNA Alkylator/Crosslinker
HBV
IAP
Integrin
Mdm2
Ras
Retinoid Receptor
ROS Kinase
SARS-CoV
Sirtuin
transporter
Tyrosinase
ATPase
CaMK
Carbonic Anhydrase
Cholinesterase (ChE)
Estrogen/progestogen Receptor
Glucosidase
GluR
Histamine Receptor
Immunology/Inflammation related
IRE1
MNK
Porcupine
S1P Receptor
SGK
ADC Cytotoxin
ACK1
Adenosine Deaminase
BACE
BCRP
Chloride channel
DHFR
Dopamine Receptor
Ephrin Receptor
GTPase
IFNAR
Kinesin
LDL
Lipid
LTR
Methionine Adenosyltransferase (MAT)
MLK
NOD
NOD-like Receptor (NLR)
Opioid Receptor
PAK
PGE Synthase
RAAS
Reverse Transcriptase
Serine/threonin kinase
Thrombin
Tie-2
TRP/TRPV Channel
UGT
Acyltransferase
AhR
Androgen Receptor
Antifolate
Aryl Hydrocarbon Receptor
ATP Citrate Lyase
Beta-Secretase
cAMP
CCR
Cholecystokinin Receptor
CRISPR/Cas9
CRM1
Discoidin Domain Receptor (DDR)
Estrogen Receptor/ERR
Fatty Acid Synthase
Glutathione Peroxidase
GPCR
GRK
Hck
Hippo pathway
KSP
Leukotriene Receptor
Liver X Receptor
MAO
Monoamine Transporter
NADPH
NAMPT
NEDD8
NMDAR
PERK
Phospholipase
PYK2
RIP kinase
Serine Protease
SGLT
Survivin
TOPK
Transferase
ABC Transporter
Adenylyl Cyclase
Amino Acids and Derivatives
Arginase
Aromatase
BMI-1
CFTR
Cuproptosis
DAPK
Decarboxylase
DNA
DNA gyrase
FAAH
Factor Xa
Free radical scavengers
FXR
Glucocorticoid Receptor
Glucokinase
Glutaminase
gp120/CD4
GST
Guanylate cyclase
Haspin Kinase
hCE
Imidazoline Receptor
KLF
Lipase
LPL Receptor
LRRK2
MALT
Melanin-concentrating Hormone Receptor (MCHR)
MicroRNA
Monocarboxylate transporter
MRP
MyD88
Myosin
Na+/Ca2+ Exchanger
NADPH-oxidase
Neprilysin
NPC1L1
NUDIX hydrolase
OCT
OXPHOS
p97
PAD
PKM
Platelet aggregation
Progesterone Receptor
PROTACs
Protease
Protease-activated Receptor
Proton pump
RAR/RXR
Reductase
ROR
RSV
Sigma receptor
STING
Telomerase
Thrombopoietin Receptor
Wee1
YAP