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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases. Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
NF-κB
PI3K
EGFR
HDAC
Wnt/beta-catenin
mTOR
JAK
Akt
STAT
FLT
AMPK
GSK-3
Antibacterial
Bcl-2 Family
Endogenous Metabolite
VEGFR
CDK
c-Kit
Proteasome
Bcr-Abl
PDGFR
HIF/HIF Prolyl-Hydroxylase
Histone Methyltransferase
Src
HER
HIF
COX
Dehydrogenase
ERK
Tyrosine Kinases
DNA/RNA Synthesis
Hedgehog/Smoothened
Antibiotic
DNA-PK
FGFR
HIV Protease
Reactive Oxygen Species
Caspase
S6 Kinase
p38 MAPK
Parasite
TNF
Epigenetic Reader Domain
ATM/ATR
Topoisomerase
DNA Methyltransferase
PARP
PKC
JNK
PDK
Pim
Potassium Channel
Aurora Kinase
Gamma-secretase
IL Receptor
Influenza Virus
PPAR
c-Met/HGFR
Ferroptosis
Microtubule Associated
Mitophagy
PD-1/PD-L1
BTK
c-RET
ALK
c-Myc
Antifungal
Raf
Virus Protease
CXCR
Cytochromes P450
MAPK
MEK
TAM Receptor
DPP-4
E1/E2/E3 Enzyme
IGF-1R
PI4K
Calcium Channel
Nrf2
p53
PKA
AChR
c-Fms
Histone Demethylase
NO Synthase
Smo
Antioxidant
Antiviral
Casein Kinase
Chk
HCV Protease
Nucleoside Antimetabolite/Analog
Phosphatase
Syk
Trk receptor
Beta Amyloid
Isocitrate Dehydrogenase (IDH)
IκB/IKK
Lipoxygenase
Interleukin
MMP
PLK
TLR
FAK
PDE
P-gp
ROS
Sodium Channel
Adenosine Receptor
CSF-1R
Drug Metabolite
HSP
NOS
PTEN
5-HT Receptor
Antifection
DYRK
GABA Receptor
Histone Acetyltransferase
Mitochondrial Metabolism
SIK
Anti-infection
Cysteine Protease
DUB
HSV
IRAK
MELK
Prostaglandin Receptor
Retinoid Receptor
Rho
ROCK
SARS-CoV
Sirtuin
TGF-beta/Smad
Adrenergic Receptor
Aminopeptidase
CaMK
Cannabinoid Receptor
DNA Alkylation
Estrogen/progestogen Receptor
GluR
IAP
Immunology/Inflammation related
Integrin
Mdm2
ROS Kinase
transporter
Tyrosinase
ATPase
Carbonic Anhydrase
Chloride channel
Cholinesterase (ChE)
DNA Alkylator/Crosslinker
Glucosidase
HBV
Histamine Receptor
MNK
Porcupine
Ras
S1P Receptor
TRP/TRPV Channel
ADC Cytotoxin
ACK1
Adenosine Deaminase
BACE
BCRP
DHFR
Dopamine Receptor
Ephrin Receptor
Estrogen Receptor/ERR
GTPase
IFNAR
IRE1
Kinesin
LDL
Lipid
LTR
MAO
Methionine Adenosyltransferase (MAT)
NMDAR
NOD
NOD-like Receptor (NLR)
PAK
PGE Synthase
RAAS
Reverse Transcriptase
Serine/threonin kinase
SGK
Thrombin
Tie-2
UGT
Acyltransferase
AhR
Amino Acids and Derivatives
Androgen Receptor
Antifolate
Aryl Hydrocarbon Receptor
ATP Citrate Lyase
Beta-Secretase
cAMP
CCR
Cholecystokinin Receptor
CRISPR/Cas9
CRM1
Discoidin Domain Receptor (DDR)
Fatty Acid Synthase
Glutathione Peroxidase
GPR
GRK
Hck
Hippo pathway
KSP
Leukotriene Receptor
Liver X Receptor
MLK
Monoamine Transporter
NADPH
NAMPT
NEDD8
Opioid Receptor
Phospholipase
PYK2
RIP kinase
Serine Protease
SGLT
Survivin
TOPK
Transferase
ABC Transporter
Adenylyl Cyclase
Arginase
Aromatase
BMI-1
CFTR
Cuproptosis
DAPK
Decarboxylase
DNA
DNA gyrase
Factor Xa
Free radical scavengers
FXR
Glucocorticoid Receptor
Glucokinase
Glutaminase
gp120/CD4
GST
Guanylate cyclase
Haspin Kinase
hCE
Imidazoline Receptor
KLF
Lipase
LPL Receptor
MALT
Melanin-concentrating Hormone Receptor (MCHR)
MicroRNA
Monoamine Oxidase
Monocarboxylate transporter
MRP
MyD88
Myosin
Na+/Ca2+ Exchanger
NADPH-oxidase
Neprilysin
NPC1L1
NUDIX hydrolase
OCT
OXPHOS
p97
PAD
PERK
PKM
Platelet aggregation
Progesterone Receptor
PROTACs
Protease
Protease-activated Receptor
Proton pump
RAR/RXR
Reductase
ROR
RSV
Sigma receptor
STING
Telomerase
Thrombopoietin Receptor
Wee1
YAP