GDF-15 Protein, Rat, Recombinant (His)

Name: GDF-15 Protein, Rat, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01243
Price: 79 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: RG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15) Copy Product Info

Synonyms: RG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15

Catalog No. TMPK-01243 Copy Product Info

Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.

Pack Size	Price	USA Stock	Global Stock
5 µg	$79	-	In Stock
10 µg	$128	7-10 days	7-10 days
20 µg	$209	-	In Stock
50 µg	$415	-	In Stock
100 µg	$698	-	In Stock
200 µg	$1,260	7-10 days	7-10 days
500 µg	$2,800	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:> 95%

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Immobilized Rat GDF-15, His Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 8.0 ng/mL determined by ELISA. 2. Immobilized Rat GDF15, His Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Biotinylated Mouse GFRAL, His Tag with the EC50 of 0.95 μg/mL determined by ELISA.
Description	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.
Species	Rat
Expression System	E. coli
Tag	N-His
Accession Number	Q9Z0J6
Construction	Ser189-Ala303
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM HAc (pH 2.9). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	RG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15
Research Background	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.

Chemical Properties

Molecular Weight

13.68 kDa (predicted). The protein migrates to 15-17 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.