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GDF-15 Protein, Rat, Recombinant (His)

(Synonyms: RG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15) Copy Product Info

Synonyms: RG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15

Catalog No. TMPK-01243 Copy Product Info
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.

Batch Information

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Purity:> 95%
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Product Introduction

Bioactivity
Description
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.
Species
Rat
Expression System
E. coli
TagN-His
Accession NumberQ9Z0J6
ConstructionSer189-Ala303
Protein Purity
> 95% as determined by Tris-Bis PAGE
https://cdn.targetmol.com/group3/M00/3E/DF/CgoaEWbGogmEGHEWAAAAAHfpYmg869.png
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM HAc (pH 2.9). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsRG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15
Research Background
Chemical Properties
Molecular Weight13.68 kDa (predicted). The protein migrates to 15-17 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: GDF-15 Protein, Rat, Recombinant (His) chemical structure | GDF-15 Protein, Rat, Recombinant (His) molecular weight