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Anti-IL-1 alpha/IL1A Antibody (5R998)

🥰Excellent
Catalog No. TMAY-03112

Anti-IL-1 alpha/IL1A Antibody (5R998) is a Rabbit antibody targeting IL-1 alpha/IL1A. Anti-IL-1 alpha/IL1A Antibody (5R998) can be used in ELISA.

Anti-IL-1 alpha/IL1A Antibody (5R998)

Anti-IL-1 alpha/IL1A Antibody (5R998)

🥰Excellent
Catalog No. TMAY-03112
Anti-IL-1 alpha/IL1A Antibody (5R998) is a Rabbit antibody targeting IL-1 alpha/IL1A. Anti-IL-1 alpha/IL1A Antibody (5R998) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-IL-1 alpha/IL1A Antibody (5R998) is a Rabbit antibody targeting IL-1 alpha/IL1A. Anti-IL-1 alpha/IL1A Antibody (5R998) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
5R998
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-1 alpha / IL-1F1 / IL1A (rM IL-1 alpha / IL-1F1 / IL1A; TMPY-01738; NP_034684.2; Ser 115-Ser 270).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. Cytokines can be classified into two groups: pro- and anti-inflammatory. Pro-inflammatory cytokines, including IFNgamma, IL-1, IL-6, and TNF-alpha, are predominantly derived from the innate immune cells and Th1 cells. Anti-inflammatory cytokines, including IL-10, IL-4, IL-13, and IL-5, are synthesized from Th2 immune cells. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. It is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse IL-1 alpha / IL-1F1 / IL1A protein (TMPY-01738)
Antigen Species
Mouse
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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