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Anti-Vimentin Antibody (9B786) is a Rabbit antibody targeting Vimentin. Anti-Vimentin Antibody (9B786) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Human |
Alias | vimentin, HEL113, CTRCT30 |
Ig Type | Rabbit IgG |
Clone | 9B786 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human Vimentin in human small intestine with rabbit monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human Vimentin in human thyroid gland with rabbit monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. 3. Immunochemical staining of human Vimentin in human kidney with rabbit monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:1000-1:5000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Vimentin (rh Vimentin; TMPY-04329; P08670; Met1-Glu466). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. Therefore, in general, it is accepted that vimentin is the cytoskeletal component responsible for maintaining cell integrity. Vimentin is also responsible for stabilizing cytoskeletal interactions. It is found that vimentin control the transport of low-density lipoprotein. It has been used as a sarcoma tumor marker to identify mesenchyme. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human Vimentin Protein (TMPY-04329) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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