DEFB2 Protein, Mouse, Recombinant

Name: DEFB2 Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00007
Rating: 4.5 (1 reviews)

(Synonyms: mBD-2, Defensin, beta 2, Defb2) Copy Product Info

Synonyms: mBD-2, Defensin, beta 2, Defb2

Catalog No. TMPS-00007 Copy Product Info

DEFB2 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P82020.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$123	7-10 days	7-10 days
10 µg	$198	7-10 days	7-10 days
20 µg	$339	7-10 days	7-10 days
50 µg	$625	7-10 days	7-10 days
100 µg	$996	7-10 days	7-10 days
200 µg	$1,590	7-10 days	7-10 days
500 µg	$2,960	7-10 days	7-10 days
1 mg	$4,750	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using immature human dendritic cells is in a concentration of 10-100 ng/ml.
Description	DEFB2 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P82020.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	P82020
Construction	Ala21-Lys71
Protein Purity	> 98% as determined by SDS-PAGE; > 98% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water or aqueous buffer containing 0.1% BSA. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	mBD-2, Defensin, beta 2, Defb2
Research Background	Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.

Chemical Properties

Molecular Weight

5.5 kDa (Predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.