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Anti-PTP1B Antibody (7U863)

(Synonyms: PTP1B) Copy Product Info
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Synonyms: PTP1B

Catalog No. TMAH-01021 Copy Product Info
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Anti-PTP1B Antibody (7U863) is an antibody targeting PTP1B. Anti-PTP1B Antibody (7U863) can be used in ELISA,IHC,WB.
Anti-PTP1B Antibody
(7U863)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2087-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PTP1B Antibody (7U863) is an antibody targeting PTP1B. Anti-PTP1B Antibody (7U863) can be used in ELISA,IHC,WB.
SynonymsPTP1B
Ig Type
Rabbit IgG
Clone
7U863
Reactivity
Human
Application
Recommended Dose
WB:1:500-1:5000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationEndoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with EPHA3 at the cell membrane.
Tissue SpecificityExpressed in keratinocytes (at protein level).
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundTyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human PTP1B
Antigen Species
Human
Gene Name
PTPN1
Gene ID
Uniprot ID
Biology Area
Cardiovascular, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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