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Anti-PSGL-1/CD162 Antibody (3U936)
🥰Excellent
Catalog No. TMAY-03455
Anti-PSGL-1/CD162 Antibody (3U936) is a Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (3U936) can be used in FCM.
Anti-PSGL-1/CD162 Antibody (3U936)
Anti-PSGL-1/CD162 Antibody (3U936)
🥰Excellent
Catalog No. TMAY-03455
Anti-PSGL-1/CD162 Antibody (3U936) is a Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (3U936) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PSGL-1/CD162 Antibody (3U936) is a Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (3U936) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3U936 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse SELPLG(CD162) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse SELPLG(CD162), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PSGL-1/CD162 (rM PSGL-1/CD162; TMPY-03354; Q62170; Met1-Cys307). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse PSGL-1/CD162 Protein (TMPY-03354) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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