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Anti-Phospho-APP (Thr743) Polyclonal Antibody is a Rabbit antibody targeting Phospho-APP (Thr743). Anti-Phospho-APP (Thr743) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $216 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-Phospho-APP (Thr743) Polyclonal Antibody is a Rabbit antibody targeting Phospho-APP (Thr743). Anti-Phospho-APP (Thr743) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | amyloid beta precursor protein(APP) Homo sapiens This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human Amyloid beta A4 around the phosphorylation site of Thr743/668. AA range:711-760 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 140 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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