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EP3 antagonist 3, a potent and selective EP3 antagonist with the advantage of oral activity, significantly inhibited GR63799- or acetic acid-induced reduction in bladder capacity and PGE2-induced overactive bladder model in spontaneously hypertensive rats (SHR).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $954 | 6-8 weeks | |
50 mg | $1,240 | 6-8 weeks | |
100 mg | $1,990 | 6-8 weeks |
Description | EP3 antagonist 3, a potent and selective EP3 antagonist with the advantage of oral activity, significantly inhibited GR63799- or acetic acid-induced reduction in bladder capacity and PGE2-induced overactive bladder model in spontaneously hypertensive rats (SHR). |
Targets&IC50 | EP3:8.3 (pKi) |
Molecular Weight | 362.38 |
Formula | C21H18N2O4 |
Cas No. | 1227827-88-4 |
Smiles | O=C1OC(C(=O)N1)(C2=CC=C(NC2=O)C=3C=CC=4C=CC=CC4C3)C(C)C |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 200 mg/mL (551.91 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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