Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the α4/α6 allosteric pocket and demonstrates ATP-competitive activity [1].
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Description | PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the α4/α6 allosteric pocket and demonstrates ATP-competitive activity [1]. |
Molecular Weight | 319.28 |
Formula | C13H9F4NO2S |
CAS No. | 1141768-04-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PVZB1194 1141768-04-8 Cytoskeletal Signaling Kinesin inhibitor inhibit