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Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2
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Catalog No. TMAC-01499
Alias p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253)
Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO3 (Ser253). Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody can be used in IF,IHC,WB.
Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2
Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2
😃Good
Catalog No. TMAC-01499Alias p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253)
Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO3 (Ser253). Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody can be used in IF,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO3 (Ser253). Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody can be used in IF,IHC,WB. |
| Synonyms | p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from NIH/3T3 cells using FKHRL1 (Ab-253) antibody (Lane 1 and 2) and FKHRL1 (phospho-Ser253) antibody (TMAC-01499, Lane 3 and 4). 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FKHRL1 (phospho-Ser253) antibody (TMAC-01499). 3. Immunofluorescence staining of methanol-fixed HeLa cells using FKHRL1 (phospho-Ser253) antibody (TMAC-01499, Red).    |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 253(A-V-S(p)-M-D) derived from Human FKHRL1 |
| Antigen Species | human |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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