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Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2 (Synonyms: p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253...)

Catalog No. TMAC-01499 Copy Product Info
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Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO3 (Ser253). Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody can be used in IF,IHC,WB.

Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAC-01499
Synonyms p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253)

Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO3 (Ser253). Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody can be used in IF,IHC,WB.

Anti-Phospho-FOXO3
(Ser253) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO3 (Ser253). Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody can be used in IF,IHC,WB.
Synonymsp-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from NIH/3T3 cells using FKHRL1 (Ab-253) antibody (Lane 1 and 2) and FKHRL1 (phospho-Ser253) antibody (TMAC-01499, Lane 3 and 4).
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FKHRL1 (phospho-Ser253) antibody (TMAC-01499).
3. Immunofluorescence staining of methanol-fixed HeLa cells using FKHRL1 (phospho-Ser253) antibody (TMAC-01499, Red).
verifiedActivityverifiedActivityverifiedActivity
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundTranscriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 253(A-V-S(p)-M-D) derived from Human FKHRL1
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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