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IFNAR1 Protein, Rhesus macaque, Recombinant (His)

(Synonyms: β-type antiviral protein, α-type antiviral protein, IFN-α/β receptor 1, IFN-α/β R1, IFN-alpha/beta receptor 1, IFN-alpha/beta R1, IFN-al, human interferon-α receptor (HuIFN-α-Rec)10IFRC, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, Cytokine receptor family 2 member 1, Cytokine receptor class-II member 1, CRF2-1, beta-type antiviral protein, AVP, alpha-type antiviral protein) Copy Product Info

Synonyms: β-type antiviral protein, α-type antiviral protein, IFN-α/β receptor 1, IFN-α/β R1, IFN-alpha/beta receptor 1, IFN-alpha/beta R1, IFN-al, human interferon-α receptor (HuIFN-α-Rec)10IFRC, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, Cytokine receptor family 2 member 1, Cytokine receptor class-II member 1, CRF2-1, beta-type antiviral protein, AVP, alpha-type antiviral protein

Catalog No. TMPJ-00331 Copy Product Info
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$8035 days35 days
10 μg$12935 days35 days
20 μg$19835 days35 days
50 μg$39035 days35 days
100 μg$62635 days35 days
200 μg$98735 days35 days
500 μg$1,90035 days35 days
1 mg$2,73035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
Species
Rhesus
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberA0A7N9D7J0
Amino AcidAla25-Lys437
ConstructionAla25-Lys437
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymsβ-type antiviral protein, α-type antiviral protein, IFN-α/β receptor 1, IFN-α/β R1, IFN-alpha/beta receptor 1, IFN-alpha/beta R1, IFN-al, human interferon-α receptor (HuIFN-α-Rec)10IFRC, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, Cytokine receptor family 2 member 1, Cytokine receptor class-II member 1, CRF2-1, beta-type antiviral protein, AVP, alpha-type antiviral protein
Research Background
Chemical Properties
Molecular Weight70-120 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: IFNAR1 Protein, Rhesus macaque, Recombinant (His) chemical structure | IFNAR1 Protein, Rhesus macaque, Recombinant (His) molecular weight