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PSMA Protein, Human, Recombinant (His), Biotinylated
(Synonyms: PSMA, PSM, NAALAdase, NAALAD1, mGCP, GCPII, GCP2, FOLH, folate hydrolase (prostate-specific membrane antigen) 1, FGCP) Copy Product InfoSynonyms: PSMA, PSM, NAALAdase, NAALAD1, mGCP, GCPII, GCP2, FOLH, folate hydrolase (prostate-specific membrane antigen) 1, FGCP
Catalog No. TMPY-05269 Copy Product Info
PSMA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.7 kDa and the accession number is Q04609-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $137 | 7-10 days | 7-10 days | |
| 10 µg | $230 | 7-10 days | 7-10 days | |
| 20 µg | $383 | 7-10 days | 7-10 days | |
| 50 µg | $629 | 7-10 days | 7-10 days | |
| 100 µg | $1,050 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized anti-PSMA at 2 μg/mL (100 μL/well) can bind Recombinant Human PSMA/FOLH1 Protein (His Tag), Biotinylated (Cat#TMPY-05269), the EC50 is 1.2-3.6 ng/mL. |
| Description | PSMA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.7 kDa and the accession number is Q04609-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-His |
| Accession Number | Q04609-1 |
| Construction | A DNA sequence encoding the human FOLH1 (NP_004467.1) (Lys44-Ala750) was expressed with a polyhistidine tag at the N-terminus. The purified protein was biotinylated in vitro. Predicted N terminal: His |
| Protein Purity | ≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | PSMA, PSM, NAALAdase, NAALAD1, mGCP, GCPII, GCP2, FOLH, folate hydrolase (prostate-specific membrane antigen) 1, FGCP |
| Research Background | Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. FOLH1 is highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, brain (at protein level), and the capillary endothelium of a variety of tumors. FOLH1 has both folate hydrolase and N-acetylated alpha linked acidic dipeptidase (NAALADase) activity. It has a preference for tri-alpha-glutamate peptides. Genetic variation in FOLH1 may be associated with low folate levels and consequent hyperhomocysteinemia. This condition can result in increased risk of cardiovascular disease, neural tube defects, and cognitive deficits. FOLH1 also shows a promising role in directed imaging and therapy of recurrent or metastatic disease.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Molecular Weight | 81.7 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: PSMA Protein, Human, Recombinant (His), Biotinylated chemical structure | PSMA Protein, Human, Recombinant (His), Biotinylated molecular weight
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