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Anti-CYP7A1 Polyclonal Antibody 3

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Catalog No. TMAB-00527

Anti-CYP7A1 Polyclonal Antibody 3 is a Rabbit antibody targeting CYP7A1. Anti-CYP7A1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-CYP7A1 Polyclonal Antibody 3

Anti-CYP7A1 Polyclonal Antibody 3

😃Good
Catalog No. TMAB-00527
Anti-CYP7A1 Polyclonal Antibody 3 is a Rabbit antibody targeting CYP7A1. Anti-CYP7A1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$222 7-10 days
100 μL$372 7-10 days
200 μL$528 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Polyclonal

Application: IHC-P,IHC-Fr,IF

Reactivity: Human,GuineaPig (predicted:Mouse,Rat,Pig,Rabbit)
Ig Type
IgG
Reactivity
Human,GuineaPig (predicted:Mouse,Rat,Pig,Rabbit)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded Human Liver Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CYP7A1 Polyclonal Antibody, Unconjugated (TMAB-00527) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CYP7A1 Polyclonal Antibody, Unconjugated (TMAB-00527) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
Application
IHC-P,IHC-Fr,IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CYP7A1
Antigen Species
Human
Gene ID
1581
Uniprot ID
Biology Area
Lipid metabolism,Cancer,Cytochromes,Lipid metabolism,Lipases,Cholesterol Metabolism,Cytochromes,Cholesterol Metabolism,Metabolism of lipids and lipoproteins
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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