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Guanosine 5'-diphosphate disodium salt

🥰Excellent
Catalog No. T7606Cas No. 7415-69-2
Alias 5'-GDP-Na2

Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.

Guanosine 5'-diphosphate disodium salt
Other Forms of Guanosine 5'-diphosphate disodium salt:

Guanosine 5'-diphosphate disodium salt

🥰Excellent
Purity: 99.40%
Catalog No. T7606Alias 5'-GDP-Na2Cas No. 7415-69-2
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$47In Stock
25 mg$64In Stock
50 mg$80In Stock
100 mg$108In Stock
500 mg$272In Stock
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Purity:99.40%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.
Synonyms5'-GDP-Na2
Chemical Properties
Molecular Weight487.16
FormulaC10H13N5Na2O11P2
Cas No.7415-69-2
SmilesNc1nc2c(ncn2C2OC(COP(=O)([O-])OP(=O)([O-])O)C(O)C2O)c(=O)[nH]1.[Na+].[Na+]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 50 mg/mL (102.64 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.0527 mL10.2636 mL20.5271 mL102.6357 mL
5 mM0.4105 mL2.0527 mL4.1054 mL20.5271 mL
10 mM0.2053 mL1.0264 mL2.0527 mL10.2636 mL
20 mM0.1026 mL0.5132 mL1.0264 mL5.1318 mL
50 mM0.0411 mL0.2053 mL0.4105 mL2.0527 mL
100 mM0.0205 mL0.1026 mL0.2053 mL1.0264 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Potassium ChannelKcsAK+ channelInhibitorinhibitinflammationHuman Endogenous MetaboliteHepG2hepcidinGuanosine 5'diphosphate disodium saltGuanosine 5'-diphosphate disodiumGuanosine 5'-diphosphateGuanosine 5' diphosphate disodium saltGDP disodiumEndogenousMetaboliteEndogenous MetaboliteCaco-2anemia
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