Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Cripto Antibody (6V546)

😃Good
Catalog No. TMAY-01320
Alias teratocarcinoma-derived growth factor 1, CRIPTO, CRGF, CR

Anti-Cripto Antibody (6V546) is a Mouse antibody targeting Cripto. Anti-Cripto Antibody (6V546) can be used in ELISA.

Anti-Cripto Antibody (6V546)

Anti-Cripto Antibody (6V546)

😃Good
Catalog No. TMAY-01320Alias teratocarcinoma-derived growth factor 1, CRIPTO, CRGF, CR
Anti-Cripto Antibody (6V546) is a Mouse antibody targeting Cripto. Anti-Cripto Antibody (6V546) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$198 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-Cripto Antibody (6V546) is a Mouse antibody targeting Cripto. Anti-Cripto Antibody (6V546) can be used in ELISA.
Aliasteratocarcinoma-derived growth factor 1, CRIPTO, CRGF, CR
Ig Type
Monoclonal Mouse IgG1
Clone
6V546
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cripto / TDGF1 / CRGF (rh Cripto / TDGF1 / CRGF; TMPY-01413; AAH22393.1; Met1-Thr172). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCripto/TDGF1 is a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. Before gastrulation, Cripto is asymmetrically expressed in a proximal–distal gradient in the epiblast, and subsequently is expressed in the primitive streak and newly formed embryonic mesoderm. These proteins play key roles in intercellular signaling pathways during vertebrate embryogenesis. Mutations in Cripto/TDGF1 can cause autosomal visceral heterotaxy. Cripto/TDGF1 is involved in left-right asymmetric morphogenesis during organ development. Cripto signalling is essential for the conversion of a proximal–distal asymmetry into an orthogonal anterior–posterior axis. The mechanism of inhibitory effects of the Cripto includes both cancer cell apoptosis, activation of c-Jun-NH(2)-terminal kinase and p38 kinase signaling pathways and blocking of Akt phosphorylation. Thus, Cripto is a unique target, and Immunohistochemistry to Cripto could be of therapeutic value for human cancers.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Cripto / TDGF1 / CRGF Protein (TMPY-01413)
Antigen Species
Human
Biology Area
Cardiac Stem Cell Markers
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Cripto Antibody (6V546) | purchase Anti-Cripto Antibody (6V546) | Anti-Cripto Antibody (6V546) cost | order Anti-Cripto Antibody (6V546)