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Anti-Phospho-Shc (Tyr317) Polyclonal Antibody
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Catalog No. TMAC-03734
Anti-Phospho-Shc (Tyr317) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Shc (Tyr317). Anti-Phospho-Shc (Tyr317) Polyclonal Antibody can be used in WB.
Anti-Phospho-Shc (Tyr317) Polyclonal Antibody
Anti-Phospho-Shc (Tyr317) Polyclonal Antibody
😃Good
Catalog No. TMAC-03734
Anti-Phospho-Shc (Tyr317) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Shc (Tyr317). Anti-Phospho-Shc (Tyr317) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-Shc (Tyr317) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Shc (Tyr317). Anti-Phospho-Shc (Tyr317) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | SHC adaptor protein 1(SHC1) Homo sapiens This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011], |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human Shc around the phosphorylation site of Tyr317 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 66, 52, 46 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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