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Anti-Phospho-Shc (Tyr317) Polyclonal Antibody

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Catalog No. TMAC-03734

Anti-Phospho-Shc (Tyr317) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Shc (Tyr317). Anti-Phospho-Shc (Tyr317) Polyclonal Antibody can be used in WB.

Anti-Phospho-Shc (Tyr317) Polyclonal Antibody

Anti-Phospho-Shc (Tyr317) Polyclonal Antibody

😃Good
Catalog No. TMAC-03734
Anti-Phospho-Shc (Tyr317) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Shc (Tyr317). Anti-Phospho-Shc (Tyr317) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-Shc (Tyr317) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Shc (Tyr317). Anti-Phospho-Shc (Tyr317) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research BackgroundSHC adaptor protein 1(SHC1) Homo sapiens This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Shc around the phosphorylation site of Tyr317
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 66, 52, 46 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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