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CpCDPK1/TgCDPK1-IN-1

Name: CpCDPK1/TgCDPK1-IN-1
Brand: TargetMol
SKU: T78605
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T78605Cas No. 1092788-23-2

CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.

CpCDPK1/TgCDPK1-IN-1

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Purity: 99.61%

Catalog No. T78605Cas No. 1092788-23-2

CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$245	-	In Stock
5 mg	$679	-	In Stock
10 mg	$813	-	In Stock
25 mg	$1,020	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.61%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.
Targets&IC50	TgCDPK1:5.0 nM, CpCDPK1:10 nM

Chemical Properties

Molecular Weight	303.36
Formula	C₁₈H₁₇N₅
Cas No.	1092788-23-2
Smiles	N=1C=NC2=C(C1N)C(=NN2C(C)C)C=3C=CC=4C=CC=CC4C3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (329.64 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2964 mL	16.4821 mL	32.9641 mL	164.8207 mL
5 mM	0.6593 mL	3.2964 mL	6.5928 mL	32.9641 mL
10 mM	0.3296 mL	1.6482 mL	3.2964 mL	16.4821 mL
20 mM	0.1648 mL	0.8241 mL	1.6482 mL	8.2410 mL
50 mM	0.0659 mL	0.3296 mL	0.6593 mL	3.2964 mL
100 mM	0.0330 mL	0.1648 mL	0.3296 mL	1.6482 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc