PRPS2 Protein, Human, Recombinant (His)

Catalog No. TMPY-04768

PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine stretch.

PRPS2 Protein, Human, Recombinant (His)

Catalog No. TMPY-04768

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$76	7-10 days	7-10 days
10 μg	$118	7-10 days	7-10 days
20 μg	$197	7-10 days	7-10 days
50 μg	$458	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Information

Biological Activity	Kinase activity untested
Description	PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine stretch.
Species	Human
Expression System	E. coli
Tag	C-His
Accession Number	P11908-1
Synonyms	PRSII,PRPS2,phosphoribosyl pyrophosphate synthetase 2
Construction	A DNA sequence encoding the human PRPS2 (P11908-1) (Met1-Leu318) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Met
Protein Purity	> 95 % as determined by SDS-PAGE
Molecular Weight	35.6 kDa (predicted); 36 kDa (reducing conditions)
Endotoxin	Please contact us for more information.
Formulation	Supplied as sterile PBS, pH 7.4.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine stretch.

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Keywords

PRPS-2 PRPS 2