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Anti-CD31/PECAM-1 Antibody (7B391)
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Catalog No. TMAY-00349
Alias platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791
Anti-CD31/PECAM-1 Antibody (7B391) is a Mouse antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (7B391) can be used in FCM.
Anti-CD31/PECAM-1 Antibody (7B391)
Anti-CD31/PECAM-1 Antibody (7B391)
😃Good
Catalog No. TMAY-00349Alias platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791
Anti-CD31/PECAM-1 Antibody (7B391) is a Mouse antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (7B391) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: FCM Reactivity: Human |
| Alias | platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791 |
| Ig Type | Mouse IgG1 |
| Clone | 7B391 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of anti-human CD31 on human whole blood monocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD31 / PECAM-1 (rh CD31 / PECAM-1; TMPY-00970; EAW94208.1; Met1-Lys601). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human CD31 / PECAM-1 protein (TMPY-00970) |
| Antigen Species | Human |
| Biology Area | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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