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Anti-Apolipoprotein A-I/APOA1 Antibody (4W607)
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Catalog No. TMAY-01058
Alias Lvtw-1, Ltw-1, Brp-14, apolipoprotein A-I, apoA-I, apo-AI, Apoa-1, Alp-1, 42249, 42248, 2-Sep, 1-Sep
Anti-Apolipoprotein A-I/APOA1 Antibody (4W607) is a Mouse antibody targeting Apolipoprotein A-I/APOA1. Anti-Apolipoprotein A-I/APOA1 Antibody (4W607) can be used in ICC/IF.
Anti-Apolipoprotein A-I/APOA1 Antibody (4W607)
Anti-Apolipoprotein A-I/APOA1 Antibody (4W607)
😃Good
Catalog No. TMAY-01058Alias Lvtw-1, Ltw-1, Brp-14, apolipoprotein A-I, apoA-I, apo-AI, Apoa-1, Alp-1, 42249, 42248, 2-Sep, 1-Sep
Anti-Apolipoprotein A-I/APOA1 Antibody (4W607) is a Mouse antibody targeting Apolipoprotein A-I/APOA1. Anti-Apolipoprotein A-I/APOA1 Antibody (4W607) can be used in ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ICC/IF Reactivity: Human |
| Alias | Lvtw-1, Ltw-1, Brp-14, apolipoprotein A-I, apoA-I, apo-AI, Apoa-1, Alp-1, 42249, 42248, 2-Sep, 1-Sep |
| Ig Type | Mouse IgG1 |
| Clone | 4W607 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of APOA1 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with mouse anti-Human APOA1 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). |
| Application | ICC/IF |
| Recommended Dose | ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Apolipoprotein A-I/APOA1 (rh Apolipoprotein A-I/APOA1; TMPY-03428; P02647; Asp25-Gln267). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters, and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Apolipoprotein A-I/APOA1 Protein (TMPY-03428) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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