Siglec-5 Protein, Mouse, Recombinant (hFc)

Name: Siglec-5 Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-07209
Rating: 4.5 (1 reviews)

(Synonyms: Siglecf, Siglec5) Copy Product Info

Synonyms: Siglecf, Siglec5

Catalog No. TMPY-07209 Copy Product Info

Siglec-5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q920G3.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$109	7-10 days	7-10 days
20 µg	$172	7-10 days	7-10 days
50 µg	$343	7-10 days	7-10 days
100 µg	$682	7-10 days	7-10 days
200 µg	$987	7-10 days	7-10 days
500 µg	$2,200	7-10 days	7-10 days
1 mg	$4,500	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Siglec-5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q920G3.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q920G3
Construction	A DNA sequence encoding the Mouse SIGLEC5 (Q920G3) (Met1-Leu439) was expressed with the fused Fc region of human IgG1 at the C-terminus.
Protein Purity	≥ 95% as determined by SDS-PAGE. ≥ 90% as determined by SEC-HPLC.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile 50 mM Tris, 100 mM Glycine, 200 mM Arginine, 150 mM NaCl, pH 7.5. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	Siglecf, Siglec5
Research Background	SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Chemical Properties

Molecular Weight

72.7 kDa (predicted); 92.3 kDa (reducing contition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.