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(S)-SNAP5114

Name: (S)-SNAP5114
Brand: TargetMol
SKU: T16831
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16831Cas No. 157604-55-2

(S)-SNAP5114 is a selective inhibitor of GABA transport, exhibiting IC50 values of 5 μM for hGAT-3 and 21 μM for rGAT-2, and possesses anticonvulsant properties.

(S)-SNAP5114

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Purity: 97%

Catalog No. T16831Cas No. 157604-55-2

(S)-SNAP5114 is a selective inhibitor of GABA transport, exhibiting IC50 values of 5 μM for hGAT-3 and 21 μM for rGAT-2, and possesses anticonvulsant properties.

Pack Size	Price	Availability
5 mg	$44	In Stock
10 mg	$71	In Stock
25 mg	$163	In Stock
50 mg	$237	In Stock
100 mg	$343	In Stock
200 mg	$469	In Stock
1 mL x 10 mM (in DMSO)	$47	In Stock

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Batch Information

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Purity:97%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	(S)-SNAP5114 is a selective inhibitor of GABA transport, exhibiting IC50 values of 5 μM for hGAT-3 and 21 μM for rGAT-2, and possesses anticonvulsant properties.
Targets&IC50	GAT-3 (human):5 μM, GAT-2 (rat):21 μM

Chemical Properties

Molecular Weight	505.6
Formula	C₃₀H₃₅NO₆
Cas No.	157604-55-2
Smiles	COc1ccc(cc1)C(OCCN1CCC[C@@H](C1)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1
Relative Density.	1.175 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90.0 mg/mL (178.0 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9778 mL	9.8892 mL	19.7785 mL	98.8924 mL
5 mM	0.3956 mL	1.9778 mL	3.9557 mL	19.7785 mL
10 mM	0.1978 mL	0.9889 mL	1.9778 mL	9.8892 mL
20 mM	0.0989 mL	0.4945 mL	0.9889 mL	4.9446 mL
50 mM	0.0396 mL	0.1978 mL	0.3956 mL	1.9778 mL
100 mM	0.0198 mL	0.0989 mL	0.1978 mL	0.9889 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc