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Polatuzumab vedotin

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Catalog No. T77823Cas No. 1313206-42-6

Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows promise for research into Large B-cell lymphomas (LBCL) [1].

Polatuzumab vedotin

Polatuzumab vedotin

😃Good
Catalog No. T77823Cas No. 1313206-42-6
Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows promise for research into Large B-cell lymphomas (LBCL) [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$6882-4 weeks2-4 weeks
5 mg$2,0902-4 weeks2-4 weeks
10 mgPreferential2-4 weeks2-4 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows promise for research into Large B-cell lymphomas (LBCL) [1].
In vivo
Polatuzumab vedotin, at doses of 0.3, 1, 3, 6, and 12 mg/kg administered intravenously (i.v.) in a single administration, demonstrates anti-tumor activity in a mouse xenograft model of WSU-DLCL2 human diffuse large B-cell lymphoma [2].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin< 1.0 EU/mg
Antigen Details
TargetCD79b
Chemical Properties
Cas No.1313206-42-6
Storage & Solubility Information
Storage-20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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