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Polatuzumab vedotin

Catalog No. T77823 Copy Product Info
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Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows promise for research into Large B-cell lymphomas (LBCL) [1].

Polatuzumab vedotin

Copy Product Info
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Catalog No. T77823

Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows promise for research into Large B-cell lymphomas (LBCL) [1].

Polatuzumab vedotin
Cas No. 1313206-42-6
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$6882-4 weeks2-4 weeks
5 mg$2,0902-4 weeks2-4 weeks
10 mgPreferential2-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows promise for research into Large B-cell lymphomas (LBCL) [1].
In vivo
Polatuzumab vedotin, at doses of 0.3, 1, 3, 6, and 12 mg/kg administered intravenously (i.v.) in a single administration, demonstrates anti-tumor activity in a mouse xenograft model of WSU-DLCL2 human diffuse large B-cell lymphoma [2].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Antigen Details
TargetCD79b
Chemical Properties
Cas No.1313206-42-6
Storage & Solubility Information
Storage-20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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