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DNP-INT

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Catalog No. T36792Cas No. 69311-70-2

DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM). It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 μM, respectively.

DNP-INT

DNP-INT

😃Good
Catalog No. T36792Cas No. 69311-70-2
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM). It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 μM, respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$68635 days35 days
25 mg$2,69035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM). It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 μM, respectively.
Chemical Properties
Molecular Weight487.2
FormulaC16H14IN3O7
Cas No.69311-70-2
Relative Density.1.715g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 10 mg/mL (20.53 mM), Sonication is recommended.
DMSO: 5 mg/mL (10.26 mM), Sonication is recommended.
DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL (1.03 mM), Sonication is recommended.
Solution Preparation Table
DMF:PBS(pH 7.2)(1:1)/DMSO/DMF
1mg5mg10mg50mg
1 mM2.0525 mL10.2627 mL20.5255 mL102.6273 mL
DMSO/DMF
1mg5mg10mg50mg
5 mM0.4105 mL2.0525 mL4.1051 mL20.5255 mL
10 mM0.2053 mL1.0263 mL2.0525 mL10.2627 mL
DMF
1mg5mg10mg50mg
20 mM0.1026 mL0.5131 mL1.0263 mL5.1314 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DNP-INTDNPINTDNP INT
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