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Anti-Transferrin Receptor/TFRC Antibody (2H693)
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Catalog No. TMAY-03441
Alias transferrin receptor
Anti-Transferrin Receptor/TFRC Antibody (2H693) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (2H693) can be used in IHC-P.
Anti-Transferrin Receptor/TFRC Antibody (2H693)
Anti-Transferrin Receptor/TFRC Antibody (2H693)
😃Good
Catalog No. TMAY-03441Alias transferrin receptor
Anti-Transferrin Receptor/TFRC Antibody (2H693) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (2H693) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Transferrin Receptor/TFRC Antibody (2H693) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (2H693) can be used in IHC-P. |
| Alias | transferrin receptor |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2H693 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunochemical staining of mouse TFRC in mouse liver with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of mouse TFRC in mouse kidney with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 3. Immunochemical staining of mouse TFRC in mouse small intestine with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Transferrin Receptor / TFRC (rM Transferrin Receptor / TFRC; TMPY-02294; Q62351; Cys89-Phe763). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse Transferrin Receptor / TFRC Protein (TMPY-02294) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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