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PAT-IN-1, a protein acyl transferases (PAT) inhibitor, competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 13) [1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | PAT-IN-1, a protein acyl transferases (PAT) inhibitor, competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 13) [1]. |
| In vitro | PAT-IN-1 (compound 13) completely inhibits the growth of RJY1941 (control) at 20 μM, with no detectable effect at lower concentrations. At 5 μM, PAT-IN-1 inhibits 100% of the growth of RJY1942 (palmitoylation-sensitive) [1]. |
| Molecular Weight | 681.05 |
| Formula | C45H68N4O |
| Cas No. | 2066571-97-7 |
| Smiles | C([C@@H]1N(CC(C)C2=CC=C(CC(C)C)C=C2)CCN(CCCC[C@@H]3N(CC(C)C4=CC=C(CC(C)C)C=C4)CCNC3)C1)C5=CC=C(O)C=C5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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