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Anti-SULT1A1 Antibody (3U284)
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Catalog No. TMAY-01967
Alias TSPST1, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1, STP1, STP, ST1A3, ST1A1, PST, P-PST, HAST1/HAST2
Anti-SULT1A1 Antibody (3U284) is a Rabbit antibody targeting SULT1A1. Anti-SULT1A1 Antibody (3U284) can be used in IHC-P,ICC/IF.
Anti-SULT1A1 Antibody (3U284)
Anti-SULT1A1 Antibody (3U284)
😃Good
Catalog No. TMAY-01967Alias TSPST1, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1, STP1, STP, ST1A3, ST1A1, PST, P-PST, HAST1/HAST2
Anti-SULT1A1 Antibody (3U284) is a Rabbit antibody targeting SULT1A1. Anti-SULT1A1 Antibody (3U284) can be used in IHC-P,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P, ICC/IF Reactivity: Human |
| Alias | TSPST1, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1, STP1, STP, ST1A3, ST1A1, PST, P-PST, HAST1/HAST2 |
| Ig Type | Rabbit IgG |
| Clone | 3U284 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human SULT1A1 in human cirrhosis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SULT1A1 in human brain with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 3. Immunofluorescence staining of SULT1A1 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Y SULT1A1 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| Application | IHC-P,ICC/IF |
| Recommended Dose | IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SULT1A1 (rh SULT1A1; TMPY-02062; P50225-1; Glu2-Leu295). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Particularly SULT1A1 (Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), a member of the sulfotransferase 1 subfamily, which is a major pathway for drug metabolism in humans. Humans have at least 10 functional SULT genes. There has been an explosion in information on sulfotransferase polymorphisms and their functional consequences. An Arg213His polymorphism in SULT1A1 has a strong influence on the level of enzyme protein and activity in platelets, which have been widely used for phenotyping. Statistically significant associations were observed between the SULT1A1 genotype (Arg213His) and age, obesity and certain neoplasias (mammary, pulmonary, esophageal and urothelial cancer). Furthermore, the polymorphism of the SULT1A1 may be closely associated with breast cancer. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SULT1A1 protein (TMPY-02062) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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