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Vidarabine phosphate

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Catalog No. T20048Cas No. 29984-33-6

Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.

Vidarabine phosphate

Vidarabine phosphate

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Purity: 99.75%
Catalog No. T20048Cas No. 29984-33-6
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30In StockIn Stock
10 mg$39In StockIn Stock
25 mg$80In StockIn Stock
50 mg$122In StockIn Stock
100 mg$189In StockIn Stock
200 mg$278In StockIn Stock
500 mg$475In StockIn Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.75%
Appearance:Solid
Color:White
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Product Introduction

Vidarabine phosphate AI Summary
Vidarabine phosphate exhibits a range of bioactivities based on the research data provided. It shows inhibitory effects on the proliferation of various cancer cell lines, including Murine Leukemia, Murine Mammary Carcinoma, Human B-Lymphoblast, and Human T-Lymphoblast cells, with ID50 values ranging from 18.5 to 32.6 µg/mL. Additionally, it demonstrates antiviral activity against different strains of Herpes Simplex virus type 1 and type 2, as well as vaccinia virus and vesicular stomatitis virus, with minimum inhibitory concentrations (MIC) as low as 0.2 µg/mL. Importantly, it has minimum cytotoxic effects on certain cell lines, with the minimum cytotoxic concentration (MCC) being equal to or greater than 200.0 µg/mL in some cases..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.
Chemical Properties
Molecular Weight347.22
FormulaC10H14N5O7P
Cas No.29984-33-6
SmilesNc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O
Relative Density.2.32 g/cm3
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 12 mg/mL (34.56 mM), Sonication is recommended.
H2O: 1.61 mg/mL (4.64 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.88 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.8800 mL14.4001 mL28.8002 mL144.0009 mL
DMSO
1mg5mg10mg50mg
5 mM0.5760 mL2.8800 mL5.7600 mL28.8002 mL
10 mM0.2880 mL1.4400 mL2.8800 mL14.4001 mL
20 mM0.1440 mL0.7200 mL1.4400 mL7.2000 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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