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Anti-Nectin-2 Antibody-PE (1J223) is a PE-conjugated Rabbit antibody targeting Nectin-2. Anti-Nectin-2 Antibody-PE (1J223) can be used in FCM.
Description | Anti-Nectin-2 Antibody-PE (1J223) is a PE-conjugated Rabbit antibody targeting Nectin-2. Anti-Nectin-2 Antibody-PE (1J223) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1J223 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of anti-Human PVRL2(CD112) on A549 cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD112 / Nectin-2 (rh CD112 / Nectin-2; TMPY-00747; NP_002847.1; Met1-Leu360) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy. |
Conjucates | PE |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Human CD112 / Nectin-2 protein (TMPY-00747) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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