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Anti-MKP-3 Antibody (2L119)

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Catalog No. TMAC-02600
Alias Serine/threonine specific protein phosphatase, PYST1, PYST 1, MKP3, Mitogen-activated protein kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, MAP kinase phosphatase 3, hide, HH19, DUSP6a, Dusp6, DUSP 6a, DUSP 6, DUS6_HUMAN, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, Dual specificity phosphatase 6 isoform a, Dual specificity phosphatase 6

Anti-MKP-3 Antibody (2L119) is a Mouse antibody targeting MKP-3. Anti-MKP-3 Antibody (2L119) can be used in WB,IP,IF,IHC-P.

Anti-MKP-3 Antibody (2L119)

Anti-MKP-3 Antibody (2L119)

😃Good
Catalog No. TMAC-02600Alias Serine/threonine specific protein phosphatase, PYST1, PYST 1, MKP3, Mitogen-activated protein kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, MAP kinase phosphatase 3, hide, HH19, DUSP6a, Dusp6, DUSP 6a, DUSP 6, DUS6_HUMAN, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, Dual specificity phosphatase 6 isoform a, Dual specificity phosphatase 6
Anti-MKP-3 Antibody (2L119) is a Mouse antibody targeting MKP-3. Anti-MKP-3 Antibody (2L119) can be used in WB,IP,IF,IHC-P.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4267-10 days
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Product Introduction

Bioactivity
Description
Anti-MKP-3 Antibody (2L119) is a Mouse antibody targeting MKP-3. Anti-MKP-3 Antibody (2L119) can be used in WB,IP,IF,IHC-P.
AliasSerine/threonine specific protein phosphatase, PYST1, PYST 1, MKP3, Mitogen-activated protein kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, MAP kinase phosphatase 3, hide, HH19, DUSP6a, Dusp6, DUSP 6a, DUSP 6, DUS6_HUMAN, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, Dual specificity phosphatase 6 isoform a, Dual specificity phosphatase 6
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of MKP-3 expression in non-transfected (A) and human MKP-3 transfected (B) 293T whole cell lysates.
2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.
Application
Recommended Dose
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q21.33 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Peptide
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 42 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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