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Anti-IL-1 alpha/IL1A Antibody (8X4)
🥰Excellent
Catalog No. TMAY-03113
Anti-IL-1 alpha/IL1A Antibody (8X4) is a Rabbit antibody targeting IL-1 alpha/IL1A. Anti-IL-1 alpha/IL1A Antibody (8X4) can be used in ELISA(Cap).
Anti-IL-1 alpha/IL1A Antibody (8X4)
Anti-IL-1 alpha/IL1A Antibody (8X4)
🥰Excellent
Catalog No. TMAY-03113
Anti-IL-1 alpha/IL1A Antibody (8X4) is a Rabbit antibody targeting IL-1 alpha/IL1A. Anti-IL-1 alpha/IL1A Antibody (8X4) can be used in ELISA(Cap).
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-1 alpha/IL1A Antibody (8X4) is a Rabbit antibody targeting IL-1 alpha/IL1A. Anti-IL-1 alpha/IL1A Antibody (8X4) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8X4 |
| Reactivity | Mouse |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL1A / IL-1A / IL-1F1 (rM IL1A / IL-1A / IL-1F1; TMPY-01738; NP_034684.2; Ser115-Ser270). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. Cytokines can be classified into two groups: pro- and anti-inflammatory. Pro-inflammatory cytokines, including IFNgamma, IL-1, IL-6, and TNF-alpha, are predominantly derived from the innate immune cells and Th1 cells. Anti-inflammatory cytokines, including IL-10, IL-4, IL-13, and IL-5, are synthesized from Th2 immune cells. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. It is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse IL1A / IL-1A / IL-1F1 Protein (TMPY-01738) |
| Antigen Species | Mouse |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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