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Others

  • Elamipretide
    TP1095736992-21-5
    Elamipretide (MTP-131) is a mitochondria-targeted antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that reduces toxic reactive oxygen species (ROS) production and stabilizes cardiolipin, with blood-brain-barrier permeability. Elamipretide is a potential therapeutic agent in the rare disease of Barnes syndrome.
    • $50
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    TargetMol | Citations Cited
  • TAXUSIN
    TN676319605-80-2
    Taxusin is a natural product form Taxus wallichiana.
    • $133
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    TargetMol | Inhibitor Hot
  • GP2-114
    T19345130783-39-0In house
    GP2-114 is a catecholamine exercise mimetic that can be used to study coronary artery disease (CAD).
    • $658
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    TargetMol | Inhibitor Hot
  • Cyanosafracin B
    T2228696996-50-8
    Cyanosafracin B (Cyanoquinonamine) is a compound which can be used in the synthesis of ecteinascidin ET-743 (an antitumor chemotherapy drug).
    • $70
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    TargetMol | Inhibitor Hot
  • Dihydroxyfumaric acid hydrate
    T4931199926-38-0
    Dihydroxyfumaric acid is a known generator of superoxide anions and by hydroxyl free radicals. Dihydroxyfumarate exposure can cause insulin inhibitory effects. It can spontaneously convert to hydroxypyruvate or to oxaloglycolate.
    • $41
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    TargetMol | Inhibitor Hot
  • Bis(2-methoxy-5-((Z)-3,4,5-trimethoxystyryl)phenyl) hydrogen phosphate
    T67906735261-22-0In house
    Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate) is a compound that is a phosphoric acid derivative of compound statins.
    • $60
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    TargetMol | Inhibitor Hot
  • Aldose reductase-IN-1
    T141751355612-71-3
    Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).
    • $70
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    TargetMol | Inhibitor Hot
  • Acecainide hydrochloride
    T357534118-92-8
    Acecainide hydrochloride (NAPA) is a major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
    • $36
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    TargetMol | Inhibitor Hot
  • (L)-Sodium lactate
    T4103867-56-1
    (L)-Sodium lactate (Sodium L-Lactate) is produced from pyruvate by the enzyme Lactate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. L-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and other organs and body fluids.
    • $39
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    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Niraparib
    T32311038915-60-4
    Niraparib (MK-4827) is a PARP inhibitor that selectively inhibits PARP1 and PARP2 (IC50=3.8/2.1 nM). Niraparib has antitumor activity, inhibits DNA damage repair, and induces apoptosis.
    • $55
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    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • SMCC-DM1
    T168991228105-51-8
    SMCC-DM1 (DM1-SMCC) (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC).
    • $97
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    TargetMol | Inhibitor Hot
  • (Iso)-Isomucronulatol 7-O-glucoside
    T384894367-43-8
    Isomucronulatol 7-O-glucoside is a biologically active isoflavone isolated from Astragalus membranaceus.
    • $81
    In Stock
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    TargetMol | Inhibitor Hot
  • Uridine
    T222158-96-8
    Uridine (Uridin), a nucleoside, consists of uracil and D-ribose by a β-N1-glycosidic bond.
    • $54
    In Stock
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    TargetMol | Inhibitor Hot
  • Lipopolysaccharides
    T11855
    Lipopolysaccharides (LPS) is a unique component of the cell wall of Gram-negative bacteria and consists of three regions: lipid A, oligosaccharide core, and O-specific polysaccharide (O-antigen). Lipopolysaccharides help maintain the integrity of the outer cell membrane and protect bacteria from damage by bile salts and lipid antibiotics. Lipopolysaccharides is a highly immunogenic antigen that can enhance immune responses and can be used for inflammation model construction.
    • $45
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    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Omaveloxolone
    T69191474034-05-3
    Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
    • $38
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    TargetMol | Inhibitor Hot
  • Ac4ManNAz
    T14093361154-30-5In house
    Ac4ManNAz is an azido-containing metabolic glycoprotein labeling reagent. It can be used to selectively modify proteins, and it can be used in cell labeling, tracking and proteomic analysis;
    • $32
    In Stock
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    TargetMol | Inhibitor Hot
  • Rituximab
    T9910174722-31-7
    Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM.
    • $229
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    TargetMol | Inhibitor Hot
  • Rapamycin
    T153753123-88-9
    Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM). Rapamycin has immunosuppressive activity and induces autophagy.
    • $30
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    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • D-Luciferin Sodium
    T19743103404-75-7
    D-Luciferin Sodium is a heterocyclic light-emitting compound and natural ligand for luciferase used to detect cell activity. The salt form of luciferin dissolves in water or other typical buffers.
    • $43
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    TargetMol | Inhibitor Hot
  • Lydicamycin
    T33031133352-27-9
    Lydicamycin is isolated from Streptomyces lydicus.
    • $1,140
    35 days
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    TargetMol | Inhibitor Hot
  • 2-Methoxybenzylamine
    T13726850-57-3
    2-Methoxybenzylamine is widely used in the synthesis of other compounds such as dyes, fragrances and plastics; it can also be used in the synthesis of bioactive compounds such as antibiotics and antifungals.
    • $50
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    TargetMol | Inhibitor Hot
  • 7-Acetoxy-4-methylcoumarin
    T70372747-05-9
    7-Acetoxy-4-methylcoumarin is a fluorescent substrate for carboxylesterases and acts as an inhibitor of GST, which can be isolated from Trigonella foenum graceum and inhibits AFB1-DNA binding.
    • $38
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    TargetMol | Inhibitor Hot
  • Compound G541-1338
    T677501189492-94-1In house
    Compound G541-1338 is a useful organic compound for research related to life sciences. The catalog number is T67750 and the CAS number is 1189492-94-1.
      Inquiry
      TargetMol | Inhibitor Hot
    • Fludrocortisone
      T1666L127-31-1In house
      Fludrocortisone (Florinef) is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency. Fludrocortisone can be used to studies on treating low blood pressure.
      • $35
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      TargetMol | Inhibitor Hot
    • 5-Ph-IAA
      T8885168649-23-8
      5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.
      • $58
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      TargetMol | Inhibitor Hot
    • Paquinimod
      T7310248282-01-1
      Paquinimod (ABR 25757) is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
      • $36
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • 1-Palmitoyl-sn-glycero-3-phosphocholine
      T871217364-16-8
      1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine for fluorescent probe design
      • $39
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      TargetMol | Inhibitor Hot
    • Specnuezhenide
      T380339011-92-2
      Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect to the seeds of wheat and Chinese cabbage.
      • $32
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      TargetMol | Inhibitor Hot
    • Salvianolic acid E
      TN2174142998-46-7
      Salvianolic acid E is a water-soluble constituent isolated from Salvia miltiorrhiza.
      • $328
      In Stock
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      TargetMol | Inhibitor Hot
    • 2-NBDG
      T14017186689-07-6
      2-NBDG is a fluorescent indicator for direct glucose uptake measurement. It is an indicator of cell viability.
      • $37
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • Olorofim
      T273001928707-56-5In house
      Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pathogenic filamentous and dimorphic fungi such as Penicillium spp, Dermatophilus spp and Fusarium spp.
      • $390
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      TargetMol | Inhibitor Hot
    • Deruxtecan
      T150981599440-13-7
      Deruxtecan is an ADC drug-linker conjugate consisting of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker for the synthesis of DS-8201 and U3-1402.
      • $139
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      TargetMol | Inhibitor Hot
    • Cy5.5
      TD0091210892-23-2
      Cy5.5 (Sulfo-Cyanine5.5) is a near-infrared fluorescent dye for labeling biomolecules such as peptides, proteins and oligonucleotides (Ex=673 nm, Em=707 nm)
      • $89
      In Stock
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • Digitonin
      T272111024-24-1
      Digitonin is a natural product of the glycoside family and is a detergent. Digitonin has antitumor activity, binds to cholesterol molecules to increase the permeability of cell membranes, and is active in the cleavage of cell membranes in a wide range of cells.
      • $29
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • Gedocarnil
      T68079109623-97-4
      Gedocarnil(ZK 113315) may be used to study diseases of the central nervous system.
      • $497 TargetMol
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      TargetMol | Inhibitor Hot
    • DCLK1-IN-1
      T84182222635-15-4
      DCLK1-IN-1 is a selective and in vivo-compatible chemical probe of the DCLK1 kinase domain .
      • $107
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      TargetMol | Inhibitor Hot
    • FIDAS-5
      T112851391934-98-7
      FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.
      • $54
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • WST-8
      T4018193149-74-5
      WST-8 is a water-soluble tetrazolium dye, the sensitivity of the WST-8(WST8)-based assay is higher than the conventional MTS-based assay.
      • $50
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      TargetMol | Inhibitor Hot
    • Salvianolic Acid C
      T3149115841-09-3
      Salvianolic Acid C is extracted from the root of Salvia miltiorrhiza, a perennial plant in the genus Salvia.
      • $36
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • γ-Tocotrienol
      T1976814101-61-2
      γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E. Itl is also a radioprotector, antioxidant. It shows antitumor and antihypertensive effects in vivo.
      • $39
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      TargetMol | Inhibitor Hot
    • SM-102
      T94102089251-47-6
      SM-102 is an ionizable amino lipid utilized in the synthesis of lipid nanoparticles (LNPs)[1]. It exhibits promise in the creation of LNPs dedicated to the transportation of mRNA-based vaccines[2].
      • $52
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      TargetMol | Inhibitor Hot
    • D-Lin-MC3-DMA
      T58231224606-06-7
      D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
      • $34
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • CBL0137 hydrochloride
      T43611197397-89-9
      CBL0137 hydrochloride (Curaxin-137 hydrochloride) activates p53 and inhibits NF-kB (EC50: 0.37 0.47 μM) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.
      • $43
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      TargetMol | Inhibitor Hot
    • ML385
      T4360846557-71-9
      ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhibition of NRF2. ML385 also exhibits anti-tumor activity.
      • $47
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • β-Nicotinamide mononucleotide
      T47211094-61-7
      β-nicotinamide mononucleotide is a product of the nicotinamide-phosphate ribosyltransferase (NAMPT) reaction. β-nicotinamide mononucleotide's actions include its role in cellular biochemical function, cardioprotection, diabetes, obesity-related complications, and Alzheimer's disease.
      • $30
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • Coelenterazine
      T680855779-48-1
      Coelenterazine (Coelenteramine) is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques.
      • $97
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • Etomoxir sodium salt
      T4535828934-41-4
      Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis. Etomoxir sodium salt has antitumor activity.
      • $55
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • Trastuzumab deruxtecan
      T366461826843-81-5
      Trastuzumab deruxtecan (T-DXd) is an antibody-activated molecule coupling (ADC) with anticancer and antitumour activity.Trastuzumab deruxtecan has been shown to have an ameliorative effect in HER2-positive breast and gastric cancers.
      • $728
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      TargetMol | Inhibitor Hot
    • Deferoxamine Mesylate
      T1637138-14-7
      Deferoxamine Mesylate (DFOM) is an iron chelator and ferroptosis inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and induces apoptosis.
      • $31
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      TargetMol | Inhibitor Hot
      TargetMol | Citations Cited
    • Evolocumab
      T99201256937-27-5
      Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).
      • $397
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      TargetMol | Inhibitor Hot