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Targetmol provides additional products related to unsegmented cell signaling pathways for researchers in the life sciences and medicine fields, including inhibitors, agonists, modulators, degraders, and more.

D-Luciferin potassium
T4139115144-35-9
D-Luciferin potassium (D-Luciferin K Salt) is a popular bioluminescent substrate of luciferase in the presence of ATP.
  • $41
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TargetMol | Inhibitor Hot
Iptacopan
T118641644670-37-0
Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM.
  • $54
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TargetMol | Inhibitor Hot
PFB-FDGlu
T39518209540-62-5In house
PFB-FDGlu is a lysosomal Glucocerebrosidase (GCase) substrate with cell-permeable specificity that is cleaved to produce fluorescein.PFB-FDGlu is often used in conjunction with a flow cytometer to measure GCase activity in living cells on an individual cell basis.
  • $152
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TargetMol | Inhibitor Hot
AZD0780
T643622455427-91-3
AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.
  • $84
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TargetMol | Inhibitor Hot
Lipopolysaccharides
T11855
Lipopolysaccharides (LPS), derived from Escherichia coli O55:B5, are essential components of the outer membrane of Gram-negative bacteria. Composed of lipid A, a core oligosaccharide, and an O-specific polysaccharide, LPS exhibits strong immunogenicity. It activates immune cells via the TLR4 receptor, induces chemotactic cell migration and cytokine secretion, and helps maintain the integrity of the bacterial outer membrane, protecting against bile salts and lipid-based antibiotics. LPS is commonly used to establish inflammatory models, including arthritis, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), and gastrointestinal disease models.
  • $45
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TargetMol | Inhibitor Hot
PEG300
T702225322-68-3
PEG300 (Polyethylene glycol 300) is a polymer formed from repeating units of ethylene glycol that is water soluble, low immunogenicity, and biocompatible. PEG300 is a neutral polymer with a molecular weight of 300.
  • $48
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TargetMol | Inhibitor Hot
Deoxynivalenol
T1509751481-10-8
Deoxynivalenol (Vomitoxin) is a mycotoxin produced by Fusarium spp. of the single trichothecene family and is commonly found in contaminated food and feed.Deoxynivalenol crosses the intestinal mucosa via a cellular bypass at the tight junctions.Deoxynivalenol transporters are unaffected by inhibitors of P-glycoprotein (PgP) or multidrug resistance-associated protein (MRP). Deoxynivalenol commonly causes diarrhea, vomiting, and gastrointestinal inflammation in humans and animals.
  • $89
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TargetMol | Inhibitor Hot
SBE-β-CD
T16858182410-00-0
SBE-β-CD (Sulfobutylether-β-Cyclodextrin) is a β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether. SBE-β-CD is widely used as a co-solvent in biological experiments.
  • $41
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TargetMol | Inhibitor Hot
D18024
T10945110406-33-2In house
D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.
  • $388
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TargetMol | Inhibitor Hot
2-NBDG
T14017186689-07-6
2-NBDG is a fluorescent indicator for direct glucose uptake measurement. It is an indicator of cell viability.
  • $35
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TargetMol | Inhibitor Hot
5-OP-RU
T853292408493-91-2In house
5-OP-RU is a MAIT-activating ligand, the major antigen of MAIT cells, a mucosal adjuvant, induces efficient enrichment of mucosal-associated invariant T cells, and can be used to study Mycobacterium tuberculosis infections.
  • $319
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Evolocumab
T99201256937-27-5
Evolocumab is an inhibitor of the humanized monoclonal antibody PCSK9. It binds to circulating PCSK9 protein, resulting in inhibition of PCSK9 binding to LDLR. It can be used in studies of hypercholesterolemia and atherosclerotic cardiovascular disease.
  • $397
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TargetMol | Inhibitor Hot
Phosal 50 PG
T19513774594-96-6
Phosal 50 PG is a co-solvent used as an emulsifier and stabilizer in the pharmaceutical and cosmetic industries.Phosal 50 PG is used as a dietary supplement.
  • $349
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TargetMol | Inhibitor Hot
Tezepelumab
T773591572943-04-4
Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.
  • $1,060
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TargetMol | Inhibitor Hot
BAY-524
T145051445830-39-6
BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).
  • $93
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TargetMol | Inhibitor Hot
Human IgG1 kappa, Isotype Control
T78242
Human IgG1 kappa, Isotype Control is a humanized IgG-like monoclonal antibody and an isotype control antibody for human IgG1κ.
  • $247
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TargetMol | Inhibitor Hot
osmi-4
T123282260791-14-6In house
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor (EC50 of 3 μM in cells) that can be used to study OGT inhibition in different human cell lines.
  • $215
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TargetMol | Inhibitor Hot
Coelenterazine h
T1499450909-86-9
Coelenterazine H is a synthetic derivative of coelenterazine (a light-emitting biomolecule).Coelenterazine h (CLZN-h) is more sensitive to Ca 2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca 2+ concentrations.
  • $62
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TargetMol | Inhibitor Hot
FITC-Dextran (MW 4000)
T18988L
FITC-dextran (MW 4000) is a fluorescein isothiocyanate (FITC) Dextran fluorescent probe (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal cell damage caused by heat shock and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as the determination of blood-brain barrier permeability and the degree of blood-brain barrier disruption.
  • $30
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TargetMol | Inhibitor Hot
Fructosylvaline
T2544110003-64-2In house
Fructosylvaline(Fru-val) is present in miso, white wine and sake and has been associated with oxidative browning of white wine and sake.
  • $83
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TargetMol | Inhibitor Hot
3X FLAG peptide
TP1274402750-12-3
3X FLAG peptide consists of three repeating Asp-Tyr-Lys-Xaa-Xaa-Asp motifs with a FLAG tag at the C-terminus of the peptide.3X FLAG peptide can be used for protein identification and purification.
  • $58
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TargetMol | Inhibitor Hot
Clozic
T1083922494-47-9In house
Clozic (ICI 55897) exhibits reversible anti-proliferative effects and can be used in studies about serving as a potential anti-arthritic agent.
  • $469
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TargetMol | Inhibitor Hot
D-(-)-3-Phosphoglyceric acid disodium
T3718580731-10-8
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in glycolysis gluconeogenesis and the biosynthesis of serine, glycine, and threonine, competitively inhibiting yeast enolase. It also functions as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.
  • $30
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TargetMol | Inhibitor Hot
thermospermine
T6006670862-11-2
Thermospermine is a structural isomer of spermine that plays a role in inhibiting xylem differentiation and can enhance the translation of SAC51 and SACL1 in Arabidopsis thaliana. Thermospermine is also used in studies as a plant growth regulator and for controlling wood biomass production.
  • $152
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TargetMol | Inhibitor Hot