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CDH3 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00559
Synonyms: CDH3, Cadherin-3, Placental Cadherin, P-Cadherin, CDHP

CDH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 88-110 KDa and the accession number is AAH41846.1.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CDH3 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 68.00
50 μg 5 days $ 211.00
500 μg 5 days $ 1,070.00
1 mg 5 days $ 1,600.00
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Biological Description
Technical Params
Product Properties
Description CDH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 88-110 KDa and the accession number is AAH41846.1.
Species Human
Expression System HEK293 Cells
Tag C-6xHis
Accession Number AAH41846.1
Synonyms CDH3, Cadherin-3, Placental Cadherin, P-Cadherin, CDHP
Amino Acid Glu25-Gly654
Construction Glu25-Gly654
Protein Purity Greater than 90% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
Molecular Weight 88-110 KDa (reducing condition)
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

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Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

CDH3 Protein, Human, Recombinant (His) CDH3 Cadherin-3 Placental Cadherin P-Cadherin CDH 3 CDH-3 CDHP recombinant recombinant-proteins proteins protein

 

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