CDH3 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00559 Copy Product Info

CDH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 88-110 KDa and the accession number is AAH41846.1.

CDH3 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00559

Copy Product Info

CDH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 88-110 KDa and the accession number is AAH41846.1.

Pack Size	Price	USA Stock	Global Stock
5 μg	$44	-	In Stock
10 μg	$68	-	In Stock
20 μg	$109	7-10 days	7-10 days
50 μg	$211	7-10 days	7-10 days
100 μg	$342	7-10 days	7-10 days
200 μg	$557	7-10 days	7-10 days
500 μg	$1,070	7-10 days	7-10 days
1 mg	$1,600	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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COA User Guide of Recombinant Proteins

Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CDH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 88-110 KDa and the accession number is AAH41846.1.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	AAH41846.1
Synonyms	Placental Cadherin,P-Cadherin,CDHP,CDH3,Cadherin-3
Amino Acid	Glu25-Gly654
Construction	Glu25-Gly654
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
Molecular Weight	88-110 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.