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Anti-COX-2 Antibody (1O260)
(Synonyms: prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2) Copy Product Info
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Synonyms: prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2
Catalog No. TMAB-00471 Copy Product Info
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Anti-COX-2 Antibody (1O260) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (1O260) can be used in IF, IHC-Fr, IHC-P, WB.
Anti-COX-2 Antibody
(1O260)
(1O260)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $272 | 7-10 days | 7-10 days | |
| 100 μL | $488 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-COX-2 Antibody (1O260) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (1O260) can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2 |
| Ig Type | IgG |
| Clone | 1O260 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | IF=1:200-500; IHC-Fr=1:200-500; IHC-P=1:200-500; WB=1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Post-translational modifications : S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009] |
| Immunogen | A synthesized peptide: human COX2 |
| Antigen Species | Human |
| Gene Name | Ptgs2 |
| Gene ID | |
| Protein Name | Prostaglandin G/H synthase 2 |
| Uniprot ID | |
| Biology Area | Hormone biosynthesis,Tumor biomarkers,Lipoprotein metabolism,Platelets,Cholesterol Metabolism,Macrophage / Inflamm.,Hormone biosynthesis,Cholesterol Metabolism,Lipoprotein metabolism,Heart disease,Prostaglandins |
| Function | Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. |
| Molecular Weight | Theoretical: 65 kDa. Actual: 65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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