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KPNA2 Protein, Human, Recombinant (His)

Catalog No. TMPJ-01006
Synonyms: RCH1, SRP1-Alpha, Importin Subunit Alpha-2, Importin Subunit α-2, Karyopherin Subunit α-2, SRP1, SRP1-α, Karyopherin Subunit Alpha-2, KPNA2, RAG Cohort Protein 1

Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.

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KPNA2 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.
Species Human
Expression System E. coli
Tag N-6His
Accession Number P52292
Synonyms RCH1, SRP1-Alpha, Importin Subunit Alpha-2, Importin Subunit α-2, Karyopherin Subunit α-2, SRP1, SRP1-α, Karyopherin Subunit Alpha-2, KPNA2, RAG Cohort Protein 1
Amino Acid Met1-Phe529
Construction Recombinant Human Karyopherin Subunit Alpha-2 is produced by our E.coli expression system and the target gene encoding Met1-Phe529 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 46-63 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 20% Glycerol, pH 8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.

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Keywords

KPNA2 Protein, Human, Recombinant (His) RCH1 Importin Subunit a-2 KPNA-2 SRP1-Alpha Importin Subunit Alpha-2 Importin Subunit α-2 Karyopherin Subunit α-2 SRP1 RCH 1 RCH-1 Karyopherin Subunit a-2 SRP1-α Karyopherin Subunit Alpha-2 KPNA2 SRP 1 KPNA 2 SRP-1 RAG Cohort Protein 1 recombinant recombinant-proteins proteins protein

 

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