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2-Desoxy-4-epi-pulchellin

Name: 2-Desoxy-4-epi-pulchellin
Brand: TargetMol
SKU: TN2755
Price: 543 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2755Cas No. 122872-03-1

2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).

2-Desoxy-4-epi-pulchellin

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Purity: 99.89%

Catalog No. TN2755Cas No. 122872-03-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$60	-	In Stock
5 mg	$147	-	In Stock
10 mg	$218	-	In Stock
25 mg	Preferential	-	In Stock
50 mg	$543	-	In Stock
1 mL x 10 mM (in DMSO)	$138	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.89%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

In vitro

Dicarabrol (1), as well as three known sesquiterpenes (2-4), had potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7 μM, while they showed significant antiviral (H1N1 and H3N2) activities. Furthermore, compounds 1, 3 and 4 displayed significant antimycobacterial activity (IC50 3.7, 6.0, and 7.6 μM, respectively).

Chemical Properties

Molecular Weight	250.33
Formula	C₁₅H₂₂O₃
Cas No.	122872-03-1
Smiles	[H][C@]12C[C@@H](C)[C@]3([H])CC[C@H](O)[C@@]3(C)C[C@]1([H])C(=C)C(=O)O2
Relative Density.	1.14 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (219.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9947 mL	19.9736 mL	39.9473 mL	199.7363 mL
5 mM	0.7989 mL	3.9947 mL	7.9895 mL	39.9473 mL
10 mM	0.3995 mL	1.9974 mL	3.9947 mL	19.9736 mL
20 mM	0.1997 mL	0.9987 mL	1.9974 mL	9.9868 mL
50 mM	0.0799 mL	0.3995 mL	0.7989 mL	3.9947 mL
100 mM	0.0399 mL	0.1997 mL	0.3995 mL	1.9974 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc