Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-EMAP-II/AIMP1 Antibody (6N985)

😃Good
Catalog No. TMAY-01037
Alias SCYE1, p43, HLD3, EMAPII, EMAP-2, EMAP2

Anti-EMAP-II/AIMP1 Antibody (6N985) is a Mouse antibody targeting EMAP-II/AIMP1. Anti-EMAP-II/AIMP1 Antibody (6N985) can be used in IHC-P.

Anti-EMAP-II/AIMP1 Antibody (6N985)

Anti-EMAP-II/AIMP1 Antibody (6N985)

😃Good
Catalog No. TMAY-01037Alias SCYE1, p43, HLD3, EMAPII, EMAP-2, EMAP2
Anti-EMAP-II/AIMP1 Antibody (6N985) is a Mouse antibody targeting EMAP-II/AIMP1. Anti-EMAP-II/AIMP1 Antibody (6N985) can be used in IHC-P.
Pack SizePriceAvailabilityQuantity
100 μL$198 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-EMAP-II/AIMP1 Antibody (6N985) is a Mouse antibody targeting EMAP-II/AIMP1. Anti-EMAP-II/AIMP1 Antibody (6N985) can be used in IHC-P.
AliasSCYE1, p43, HLD3, EMAPII, EMAP-2, EMAP2
Ig Type
Monoclonal Mouse IgG1
Clone
6N985
Reactivity
Human
Verified Activity
Immunochemical staining of human SCYE1 in human brain with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:20-1:80
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human AIMP1 / EMAP II (rh AIMP1 / EMAP II; TMPY-01461; NP_004748.2; Ala2-Lys312). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAminoacyl tRNA synthase complex-interacting multifunctional protein 1, also known as Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide II, AIMP1, EMAP2 and SCYE1, is a nucleus protein which contains one tRNA-binding domain. AIMP1 (also known as p43) is a factor associated with a macromolecular aminoacyl-tRNA synthetase (ARS) complex but also plays diverse regulatory roles in various physiological processes. AIMP1 negatively regulates TGF-beta signaling via stabilization of Smurf2. It suggests the novel activity of AIMP1 as a component of negative feedback loop of TGF-beta signaling. Recently, it been demonstrated that AIMP1 is also secreted and acts as a novel pleiotropic cytokine. AIMP1 protein induces the maturation and activation of DCs, which skew the immune response toward a Th1 response. AIMP1 is known as a cytokine working in the control of angiogenesis, inflammation, and wound healing. AIMP1 is secreted from the pancreas upon glucose starvation, and it also plays a glucagon-like role in glucose homeostasis. Although AIMP1 was identified as a component of the macromolecular aminoacyl tRNA synthetase complex involved in the cellular translation process, it was also found to be secreted as a cytokine having complex physiological functions. Among these, AIMP1's angiostatic and immune stimulating activities suggest its potential use as a novel antitumor therapeutic protein. AIMP1 may exert its antitumor activity by inducing tumor-suppressing cytokines. Thus, AIMP1 may be useful as a novel anti-tumor agent.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human AIMP1 / EMAP II Protein (TMPY-01461)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-EMAP-II/AIMP1 Antibody (6N985) | purchase Anti-EMAP-II/AIMP1 Antibody (6N985) | Anti-EMAP-II/AIMP1 Antibody (6N985) cost | order Anti-EMAP-II/AIMP1 Antibody (6N985)