CLEC4A Protein, Human, Recombinant (hFc)

Name: CLEC4A Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-00126
Rating: 4.5 (1 reviews)

(Synonyms: LLIR, HDCGC13P, DDB27, DCIRLLIR, DCIR, CLECSF6, Clec4a2, CLEC4A, CD367) Copy Product Info

Synonyms: LLIR, HDCGC13P, DDB27, DCIRLLIR, DCIR, CLECSF6, Clec4a2, CLEC4A, CD367

Catalog No. TMPK-00126 Copy Product Info

Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. CLEC4A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is Q9UMR7-1.

CLEC4A Protein, Human, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$51	7-10 days	7-10 days
10 µg	$80	7-10 days	7-10 days
20 µg	$129	7-10 days	7-10 days
50 µg	$248	7-10 days	7-10 days
100 µg	$418	7-10 days	7-10 days
200 µg	$757	7-10 days	7-10 days
500 µg	$1,670	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human CLEC4A, hFc Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC4A Antibody, hFc Tag with the EC50 of 16.0ng/ml determined by ELISA.
Description	Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. CLEC4A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is Q9UMR7-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9UMR7-1
Construction	Gln70-Leu237
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	LLIR, HDCGC13P, DDB27, DCIRLLIR, DCIR, CLECSF6, Clec4a2, CLEC4A, CD367
Research Background	Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy.

Chemical Properties

Molecular Weight

46.7 kDa (predicted). Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.