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Mefloquine hydrochloride

🥰Excellent
Catalog No. T0860Cas No. 51773-92-3
Alias Mefloquine HCl, Mefloquin hydrochloride

Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.

Mefloquine hydrochloride
Other Forms of Mefloquine hydrochloride:
MefloquineT0860L53230-10-7
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Mefloquine hydrochloride

🥰Excellent
Purity: 99.74%
Catalog No. T0860Alias Mefloquine HCl, Mefloquin hydrochlorideCas No. 51773-92-3
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30In StockIn Stock
50 mg$42In StockIn Stock
100 mg$54In StockIn Stock
200 mg$72In StockIn Stock
500 mg$98In StockIn Stock
1 mL x 10 mM (in DMSO)$50In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.74%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
Targets&IC50
K+ channel:1 microM
SynonymsMefloquine HCl, Mefloquin hydrochloride
Chemical Properties
Molecular Weight414.77
FormulaC17H17ClF6N2O
Cas No.51773-92-3
Smiles[C@@H](O)([C@@H]1NCCCC1)c1cc(nc2c1cccc2C(F)(F)F)C(F)(F)F.Cl
Relative Density.1.383g/cm3
Storage & Solubility Information
Storagestore under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 76 mg/mL (183.23 mM), Sonication is recommended.
DMSO: 50 mg/mL (120.55 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.82 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.4110 mL12.0549 mL24.1097 mL120.5487 mL
5 mM0.4822 mL2.4110 mL4.8219 mL24.1097 mL
10 mM0.2411 mL1.2055 mL2.4110 mL12.0549 mL
20 mM0.1205 mL0.6027 mL1.2055 mL6.0274 mL
50 mM0.0482 mL0.2411 mL0.4822 mL2.4110 mL
100 mM0.0241 mL0.1205 mL0.2411 mL1.2055 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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