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15-keto Prostaglandin F2α

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Catalog No. T37991Cas No. 35850-13-6
Alias 15-keto Prostaglandin F2α, 15-keto PGF2α

15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.

15-keto Prostaglandin F2α
Other Forms of 15-keto Prostaglandin F2α:
8-iso-15-keto Prostaglandin F2αT36166191919-01-4
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15-keto Prostaglandin F2α

😃Good
Catalog No. T37991Alias 15-keto Prostaglandin F2α, 15-keto PGF2αCas No. 35850-13-6
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
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1 mg$49835 days
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Product Introduction

Bioactivity
Description
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
In vivo
15-keto Prostaglandin F2α stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively.[1] [2]
15-keto Prostaglandin F2α is 10-fold less active than PGF2α in decreasing rabbit intraocular pressure.[3]
Synonyms15-keto Prostaglandin F2α, 15-keto PGF2α
Chemical Properties
Molecular Weight352.47
FormulaC20H32O5
Cas No.35850-13-6
SmilesC(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/C(CCCCC)=O)[C@H](O)C[C@@H]1O
Relative Density.1.149 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 100 mg/mL (283.71 mM), Sonication is recommended.
Ethanol: 100 mg/mL (283.71 mM), Sonication is recommended.
DMSO: 100 mg/mL (283.71 mM), Sonication is recommended.
Solution Preparation Table
DMF/Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.8371 mL14.1856 mL28.3712 mL141.8560 mL
5 mM0.5674 mL2.8371 mL5.6742 mL28.3712 mL
10 mM0.2837 mL1.4186 mL2.8371 mL14.1856 mL
20 mM0.1419 mL0.7093 mL1.4186 mL7.0928 mL
50 mM0.0567 mL0.2837 mL0.5674 mL2.8371 mL
100 mM0.0284 mL0.1419 mL0.2837 mL1.4186 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

ProstaglandinReceptorProstaglandin ReceptorEndogenousMetaboliteEndogenous Metabolite15-keto Prostaglandin F2alpha15-keto Prostaglandin F2a15-keto PGF2alpha15-keto PGF2a
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