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Leptomycin B (GMP) refers to the GMP grade reagents of Leptomycin B. Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.
Description | Leptomycin B (GMP) refers to the GMP grade reagents of Leptomycin B. Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. |
Molecular Weight | 540.73 |
Formula | C33H48O6 |
Cas No. | 87081-35-4 |
Relative Density. | 1.072 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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