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Home News Center

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12 Jul 2024


20-Hydroxyeicosatetraenoic acid (hereinafter referred to as '20-HETE') is a long-chain fatty acid containing 20 carbon atoms.20-HETE is a metabolite of arachidonic acid (AA). AA, under the catalysis of the cytochrome P450 (CYP450) enzyme system, particularly the CYP4F2 enzyme, undergoes ω-hydroxylation to introduce a hydroxyl group at the C-20 position, thereby generating 20-HETE. The presence of this hydroxyl group distinguishes 20-HETE from other arachidonic acid metabolites and is crucial for its physiological and pathophysiological functions.

28 Jun 2024


Cisplatin (CDDP), chemically known as cis-diamminedichloroplatinum(II), has the molecular formula PtCl₂(NH₃)₂. Cisplatin features a divalent platinum ion as the central ion, coordinated in a square planar configuration with four dsp² hybrid orbitals of platinum acting as empty orbitals. These orbitals accept lone pairs of electrons provided by two ammonia molecules and two chloride ions, forming a square planar coordination complex. In this molecular structure, the two ammonia molecules and the two chloride ions are positioned on the same side of the square plane, creating a cis configuration. This cis configuration is crucial for cisplatin's anticancer activity[1].

25 Jun 2024

WIKIMOLE—Puromycin dihydrochloride

Puromycin dihydrochloride, catalog number T2219, also known as Puromycin 2HCl or CL13900 dihydrochloride, is the salt form of puromycin. Under identical experimental conditions, compounds in their salt form exhibit the same biological activity as their free base counterparts at the same molar concentration. However, Puromycin dihydrochloride typically has better water solubility and stability compared to the free base form.

WIKIMOLE—Puromycin dihydrochloride
14 Jun 2024


3-Methyladenine (Catalog No. T1879), also known as 3-MA, 3-Methyladenine, and NSC 66389, is a PI3K inhibitor that exerts its autophagy-inhibiting effects by inhibiting PI3K. It plays an important role in the study of cell signaling and autophagy processes.

05 Jun 2024

Meet TargetMol at EACR 2024 Congress

Meet TargetMol at EACR 2024 Congress

Meet TargetMol at EACR 2024 Congress
24 May 2024


Osimertinib is an orally available, third-generation EGFR inhibitor (EGFR-TKI) widely used for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations.

26 Apr 2024


Venetoclax, Catalog number T2119, also known as GDC-0199, ABT 199, Venclexta, ABT-199, and ABT199. Venetoclax is a Bcl-2 inhibitor (Ki <0.01 nM) with high potency, selectivity, and oral activity. Venetoclax can induce autophagy and apoptosis.

19 Apr 2024


MG-132, catalog number: T2154, also known as Z-LLL-al or Z-Leu-Leu-Leu-CHO, is a 26S proteasome inhibitor with an IC50 of 100 nM. It exhibits cell permeability and reversibility. MG-132 is capable of inducing apoptosis.

18 Apr 2024

Add 1 UDS/EURO to get a CCK-8 kit 1ml(100 tests)

Add 1 UDS/EURO to get a CCK-8 kit 1ml(100 tests)

Add 1 UDS/EURO to get a CCK-8 kit 1ml(100 tests)
12 Apr 2024

WIKIMOLE—Gastrin I, human

Gastrin I, human, Catalog Number TP2030, also known as Gastrin I (human) or Gastrin 1, is an endogenous peptide produced in the stomach. It increases gastric pepsinogen and gastric acid secretion in rats through the CCK2 receptor.

WIKIMOLE—Gastrin I, human