Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pritumumab, a natural human IgG1kappa monoclonal antibody (mAb), was first isolated from the regional draining lymph node of a cervical carcinoma patient. It specifically recognizes cell-surface-expressed vimentin on malignant tumors and has applications in glioblastoma research [1] [2].
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Description | Pritumumab, a natural human IgG1kappa monoclonal antibody (mAb), was first isolated from the regional draining lymph node of a cervical carcinoma patient. It specifically recognizes cell-surface-expressed vimentin on malignant tumors and has applications in glioblastoma research [1] [2]. |
In vivo | Pritumumab effectively inhibits tumor growth in nude mice but is ineffective in SCID mice [1]. The compound successfully constrains the growth of intracerebral xenograft glioma tumors only in the presence of a full complement of cell-mediated immunity [1]. |
Molecular Weight | N/A |
CAS No. | 499212-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pritumumab 499212-74-7 inhibitor inhibit