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Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.80 kDa and the accession number is A0A2K5WSR1.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $58 | 7-10 days | |
| 10 μg | $92 | 7-10 days | |
| 20 μg | $148 | 7-10 days | |
| 50 μg | $289 | 7-10 days | |
| 100 μg | $487 | 7-10 days | |
| 200 μg | $883 | 7-10 days | |
| 500 μg | $1,950 | 7-10 days |
| Biological Activity | Immobilized Cynomolgus DLL3, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA. |
| Description | Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.80 kDa and the accession number is A0A2K5WSR1. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | A0A2K5WSR1 |
| Synonyms | δ3,SCDO1δ3,SCDO1delta3,SCDO1,Pudgy,DLL3,Delta3 |
| Construction | Ala27-Ala477 |
| Protein Purity | > 90% as determined by Tris-Bis PAGE; > 90% as determined by SEC-HPLC |
| Molecular Weight | 48.80 kDa (predicted). Due to glycosylation, the protein migrates to 52-62 kDa based on Tris-Bis PAGE result. |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 200 mM NaCl, 200 mM L-arginine (pH 8.5). |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). |

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