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Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 2 (Synonyms: Siglec-2/CD22 (p-Y807), Siglec-2/CD22 (p-T...)
Catalog No. TMAC-00443 Copy Product Info
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Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Siglec-2/CD22 (Tyr807). Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody can be used in WB.
Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAC-00443
Synonyms Siglec-2/CD22 (p-Y807), Siglec-2/CD22 (p-Tyr807), p-Siglec-2/CD22 (Y807), p-Siglec-2/CD22 (Tyr807)
Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Siglec-2/CD22 (Tyr807). Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody can be used in WB.
Anti-Phospho-Siglec-2/CD22
(Tyr807) Polyclonal Antibody 2
(Tyr807) Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Siglec-2/CD22 (Tyr807). Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody can be used in WB. |
| Synonyms | Siglec-2/CD22 (p-Y807), Siglec-2/CD22 (p-Tyr807), p-Siglec-2/CD22 (Y807), p-Siglec-2/CD22 (Tyr807) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extracts from COS7 cells (Lane 2), using BL-CAM (Phospho-Tyr807) Antibody TMAC-00443. The lane on the left is treated with antigen-specific peptide.  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 807 (G-D-Y(p)-E-N) derived from Human BL-CAM |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 95 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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